Taking people in United StatesPhase 2
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Key facts
- Where
- ‘Aiea, ‘Ewa Beach, Abilene, Albuquerque, Allentown, Altoona, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Asheboro, Ashland, Athens, Augusta, Aurora, Aventura, Avon, Baltimore, Barrington, Battle Creek, Beachwood, Bellevue, Belpre, Bemidji, Berlin, Bethesda, Bethlehem, Billings, Birmingham, Bismarck, Bloomington, Boiling Springs, Boise, Boston, Bozeman, Brewer, Brighton, Bristol, Bryn Mawr, Buffalo, Burlington, Caldwell, Canton, Cape Girardeau, Carmichael, Carterville, Carthage, Cedar Rapids, Centerville, Centralia, Charleston, Charlottesville, Chelsea, Chesterfield, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Cleveland, Clinton, Coeur d'Alene, Collierville, Columbia, Columbus, Commack, Coon Rapids, Coral Gables, Creve Coeur, Crown Point, Crystal Lake, Cumberland, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, Deerfield Beach, DeKalb, Delaware, Des Moines, Dixon, Downers Grove, Dublin, Duluth, Durham, Easley, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, Elgin, Elk Grove, Encinitas, Erie, Escanaba, Eureka, Evanston, Fairfax, Falls Church, Fargo, Farmington, Farmington Hills, Findlay, Flemington, Flint, Fort Collins, Fort Lauderdale, Franklin, Fruitland, Gainesville, Galesburg, Geneva, Germantown, Glenview, Goldsboro, Goodyear, Grafton, Grand Rapids, Grayslake, Great Falls, Greeley, Green Bay, Greensboro, Greensburg, Greenville, Greer, Grenada, Grove City, Gulfport, Harrison, Harvey, Hazel Crest, Hazleton, Hibbing, High Point, Highland Park, Honolulu, Houston, Huntington, Issaquah, Jacksonville, Janesville, Johnson City, Jonesboro, Kalamazoo, Kalispell, Kenosha, Kettering, Kewanee, Kingman, Kingsport, La Crosse, La Jolla, Lacey, Lake Forest, Lakewood, Lancaster, Lansing, Las Vegas, Lexington, Libertyville, Livingston, Livonia, Long Branch, Los Angeles, Loveland, Lubbock, Macomb, Madison, Manistique, Mansfield, Maple Grove, Maplewood, Marinette, Marion, Marshfield, Martinez, Marysville, Mattoon, Mayfield Heights, Maywood, Mechanicsburg, Media, Memphis, Mentor, Meridian, Metairie, Miami, Michigan City, Middleburg Heights, Middletown, Milwaukee, Mineola, Minneapolis, Minocqua, Missoula, Mobile, Monroeville, Morgantown, Mount Vernon, Mukwonago, Muskegon, Nampa, Nashville, Nassau Bay, Neenah, New Albany, New Brunswick, New Lenox, New London, New Orleans, New Richmond, New York, Newark, Newberg, Newnan, Niles, Normal, North Miami, Norton Shores, O'Fallon, Oak Lawn, Oconomowoc, Oconto Falls, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Orland Park, Oshkosh, Ottawa, Oxford, Paducah, Palo Alto, Paoli, Park Ridge, Pekin, Pennington, Peoria, Perrysburg, Peru, Philadelphia, Phoenix, Pickerington, Pittsburgh, Plantation, Pontiac, Portland, Portsmouth, Post Falls, Princeton, Providence, Racine, Raleigh, Rapid City, Reed City, Reidsville, Reno, Renton, Rice Lake, Richmond, Roanoke, Rochester, Rockford, Rocklin, Rolla, Royal Oak, Sacramento, Saginaw, Saint Joseph, Saint Louis Park, Saint Paul, Sainte Genevieve, San Diego, San Francisco, Sandpoint, Sandstone, Santa Monica, Sayre, Scarborough, Seattle, Seneca, Sewell, Shawano, Sheboygan, Shiloh, Sioux Falls, Somerville, South Bend, South Hill, South Portland, Southhaven, Springfield, St Louis, Stevens Point, Stoneham, Sturgeon Bay, Sugar Land, Sullivan, Summit, Syracuse, Tawas City, Temple, The Bronx, The Woodlands, Toledo, Toms River, Traverse City, Troy, Twin Falls, Two Rivers, Urbana, Virginia, Walla Walla, Walnut Creek, Warrenville, Washington, Waukee, Waukesha, Waupaca, Wauwatosa, West Allis, West Branch, Westerville, Weston, Whittier, Willow Grove, Winston-Salem, Woodland, Wynnewood, Wyoming, Yakima, Youngstown, Ypsilanti, Zanesville, and Zion, United StatesSee the 480 sites
- Phase
- Phase 2
Where in United States
- Hawaii Cancer Care - Westridge‘Aiea, United StatesTaking people
- Pali Momi Medical Center‘Aiea, United StatesTaking people
- The Queen's Medical Center - West Oahu‘Ewa Beach, United StatesTaking people
- Hendrick Medical CenterAbilene, United StatesTaking people
- University of New Mexico Cancer CenterAlbuquerque, United StatesTaking people
- Lehigh Valley Hospital-Cedar CrestAllentown, United StatesTaking people
- UPMC AltoonaAltoona, United StatesTaking people
- Community Hospital of AnacondaAnaconda, United StatesTaking people
- Alaska Women's Cancer CareAnchorage, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, United StatesTaking people
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, United StatesTaking people
- University of Michigan Rogel Cancer CenterAnn Arbor, United StatesTaking people
- ThedaCare Regional Cancer CenterAppleton, United StatesTaking people
- ThedaCare Regional Medical Center - AppletonAppleton, United StatesTaking people
- PCR OncologyArroyo Grande, United StatesTaking people
- Cone Health MedCenter AsheboroAsheboro, United StatesTaking people
- Duluth Clinic AshlandAshland, United StatesTaking people
- OhioHealth O'Bleness HospitalAthens, United StatesTaking people
- Harold Alfond Center for Cancer CareAugusta, United StatesTaking people
- UCHealth University of Colorado HospitalAurora, United StatesTaking people
- UM Sylvester Comprehensive Cancer Center at AventuraAventura, United StatesTaking people
- UH Seidman Cancer Center at UH Avon Health CenterAvon, United StatesTaking people
- University of Maryland/Greenebaum Cancer CenterBaltimore, United StatesTaking people
- Advocate Good Shepherd HospitalBarrington, United StatesTaking people
- Bronson Battle CreekBattle Creek, United StatesTaking people
- UHHS-Chagrin Highlands Medical CenterBeachwood, United StatesTaking people
- Nebraska Medicine-BellevueBellevue, United StatesNo longer taking part
- Strecker Cancer Center-BelpreBelpre, United StatesTaking people
- Sanford Joe Lueken Cancer CenterBemidji, United StatesTaking people
- ThedaCare Cancer Care - BerlinBerlin, United StatesTaking people
- National Institutes of Health Clinical CenterBethesda, United StatesTaking people
- Walter Reed National Military Medical CenterBethesda, United StatesTaking people
- Lehigh Valley Hospital - MuhlenbergBethlehem, United StatesTaking people
- Billings Clinic Cancer CenterBillings, United StatesTaking people
- University of Alabama at Birmingham Cancer CenterBirmingham, United StatesTaking people
- Sanford Bismarck Medical CenterBismarck, United StatesTaking people
- Illinois CancerCare-BloomingtonBloomington, United StatesTaking people
- Prisma Health Cancer Institute - SpartanburgBoiling Springs, United StatesTaking people
- Saint Alphonsus Cancer Care Center-BoiseBoise, United StatesTaking people
- Saint Luke's Cancer Institute - BoiseBoise, United StatesTaking people
- Dana-Farber Cancer InstituteBoston, United StatesTaking people
- Tufts Medical CenterBoston, United StatesTaking people
- Beth Israel Deaconess Medical CenterBoston, United StatesNo longer taking part
- Bozeman Health Deaconess HospitalBozeman, United StatesTaking people
- Lafayette Family Cancer Center-EMMCBrewer, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, United StatesTaking people
- Trinity Health Medical Center - BrightonBrighton, United StatesTaking people
- University of Michigan - Brighton Center for Specialty CareBrighton, United StatesTaking people
- Ballad Health Cancer Care - BristolBristol, United StatesTaking people
- Bryn Mawr HospitalBryn Mawr, United StatesTaking people
- Roswell Park Cancer InstituteBuffalo, United StatesTaking people
- Aurora Cancer Care-Southern Lakes VLCCBurlington, United StatesTaking people
- Cone Health Cancer Center at Alamance RegionalBurlington, United StatesTaking people
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, United StatesTaking people
- Aultman Health FoundationCanton, United StatesTaking people
- Illinois CancerCare-CantonCanton, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, United StatesTaking people
- Trinity Health Medical Center - CantonCanton, United StatesTaking people
- Saint Francis Medical CenterCape Girardeau, United StatesTaking people
- Mercy Cancer Center - CarmichaelCarmichael, United StatesTaking people
- Mercy San Juan Medical CenterCarmichael, United StatesTaking people
- SIH Cancer InstituteCarterville, United StatesTaking people
- Illinois CancerCare-CarthageCarthage, United StatesTaking people
- Mercy HospitalCedar Rapids, United StatesTaking people
- Oncology Associates at Mercy Medical CenterCedar Rapids, United StatesTaking people
- Miami Valley Hospital SouthCenterville, United StatesTaking people
- Centralia Oncology ClinicCentralia, United StatesTaking people
- Vandalia Health/CAMC Institute for Academic MedicineCharleston, United StatesTaking people
- University of Virginia Cancer CenterCharlottesville, United StatesTaking people
- Chelsea HospitalChelsea, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, United StatesTaking people
- Saint Luke's HospitalChesterfield, United StatesTaking people
- Advocate Illinois Masonic Medical CenterChicago, United StatesTaking people
- John H Stroger Jr Hospital of Cook CountyChicago, United StatesTaking people
- Mount Sinai Hospital Medical CenterChicago, United StatesTaking people
- Northwestern UniversityChicago, United StatesTaking people
- University of Chicago Comprehensive Cancer CenterChicago, United StatesTaking people
- University of IllinoisChicago, United StatesTaking people
- Adena Regional Medical CenterChillicothe, United StatesTaking people
- Good Samaritan Hospital - CincinnatiCincinnati, United StatesTaking people
- Cincinnati Children's Hospital Medical CenterCincinnati, United StatesNo longer taking part
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, United StatesTaking people
- Case Western Reserve UniversityCleveland, United StatesTaking people
- Cleveland Clinic Cancer Center/Fairview HospitalCleveland, United StatesNo longer taking part
- Cleveland Clinic FoundationCleveland, United StatesNo longer taking part
- Southeastern Medical Oncology Center-ClintonClinton, United StatesTaking people
- Kootenai Health - Coeur d'AleneCoeur d'Alene, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-ColliervilleCollierville, United StatesTaking people
- Prisma Health Richland HospitalColumbia, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-Golden TriangleColumbus, United StatesTaking people
- Columbus Oncology and Hematology Associates IncColumbus, United StatesTaking people
- Doctors HospitalColumbus, United StatesTaking people
- Grant Medical CenterColumbus, United StatesTaking people
- Mount Carmel East HospitalColumbus, United StatesTaking people
- Ohio State University Comprehensive Cancer CenterColumbus, United StatesTaking people
- Riverside Methodist HospitalColumbus, United StatesTaking people
- The Mark H Zangmeister CenterColumbus, United StatesTaking people
- Memorial Sloan Kettering CommackCommack, United StatesTaking people
- Mercy HospitalCoon Rapids, United StatesTaking people
- UM Sylvester Comprehensive Cancer Center at Coral GablesCoral Gables, United StatesTaking people
- Siteman Cancer Center at West County HospitalCreve Coeur, United StatesTaking people
- UChicago Medicine Northwest IndianaCrown Point, United StatesTaking people
- AMG Crystal Lake - OncologyCrystal Lake, United StatesTaking people
- UPMC Western MarylandCumberland, United StatesTaking people
- UT Southwestern/Simmons Cancer Center-DallasDallas, United StatesTaking people
- Carle at The RiverfrontDanville, United StatesTaking people
- Miami Valley HospitalDayton, United StatesTaking people
- Miami Valley Hospital NorthDayton, United StatesTaking people
- Premier Blood and Cancer CenterDayton, United StatesTaking people
- Dayton Physician LLC - EnglewoodDayton, United StatesNo longer taking part
- Corewell Health Dearborn HospitalDearborn, United StatesTaking people
- Cancer Care Specialists of Illinois - DecaturDecatur, United StatesTaking people
- Decatur Memorial HospitalDecatur, United StatesTaking people
- Essentia Health - Deer River ClinicDeer River, United StatesTaking people
- UM Sylvester Comprehensive Cancer Center at Deerfield BeachDeerfield Beach, United StatesTaking people
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, United StatesTaking people
- Delaware Health Center-Grady Cancer CenterDelaware, United StatesTaking people
- Grady Memorial HospitalDelaware, United StatesTaking people
- Mercy Medical Center - Des MoinesDes Moines, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, United StatesTaking people
- Illinois CancerCare-DixonDixon, United StatesTaking people
- Advocate Good Samaritan HospitalDowners Grove, United StatesTaking people
- Columbus Oncology and Hematology AssociatesDublin, United StatesTaking people
- Dublin Methodist HospitalDublin, United StatesTaking people
- Epic Care-DublinDublin, United StatesNo longer taking part
- Essentia Health Cancer CenterDuluth, United StatesTaking people
- Duke University Medical CenterDurham, United StatesTaking people
- Prisma Health Cancer Institute - EasleyEasley, United StatesTaking people
- Pocono Medical CenterEast Stroudsburg, United StatesTaking people
- Marshfield Medical Center-EC Cancer CenterEau Claire, United StatesTaking people
- Fairview Southdale HospitalEdina, United StatesTaking people
- Minnesota Oncology - EdinaEdina, United StatesTaking people
- Swedish Cancer Institute-EdmondsEdmonds, United StatesTaking people
- Carle Physician Group-EffinghamEffingham, United StatesTaking people
- Crossroads Cancer CenterEffingham, United StatesTaking people
- Advocate Sherman HospitalElgin, United StatesTaking people
- Mercy Cancer Center - Elk GroveElk Grove, United StatesTaking people
- UC San Diego Health System - EncinitasEncinitas, United StatesTaking people
- UPMC Hillman Cancer Center ErieErie, United StatesTaking people
- OSF Saint Francis Hospital and Medical GroupEscanaba, United StatesTaking people
- Illinois CancerCare-EurekaEureka, United StatesTaking people
- NorthShore University HealthSystem-Evanston HospitalEvanston, United StatesTaking people
- Inova Schar Cancer InstituteFairfax, United StatesTaking people
- Inova Fairfax HospitalFalls Church, United StatesTaking people
- Sanford Broadway Medical CenterFargo, United StatesTaking people
- Sanford Roger Maris Cancer CenterFargo, United StatesTaking people
- Parkland Health Center - FarmingtonFarmington, United StatesTaking people
- Corewell Health Farmington Hills HospitalFarmington Hills, United StatesNo longer taking part
- Armes Family Cancer CenterFindlay, United StatesNo longer taking part
- Hunterdon Medical CenterFlemington, United StatesTaking people
- Cancer Hematology Centers - FlintFlint, United StatesTaking people
- Genesys Hurley Cancer InstituteFlint, United StatesTaking people
- Hurley Medical CenterFlint, United StatesTaking people
- Genesee Hematology Oncology PCFlint, United StatesNo longer taking part
- Cancer Care and Hematology-Fort CollinsFort Collins, United StatesTaking people
- Poudre Valley HospitalFort Collins, United StatesTaking people
- Broward Health Medical CenterFort Lauderdale, United StatesNo longer taking part
- Atrium Medical Center-Middletown Regional HospitalFranklin, United StatesTaking people
- Dayton Physicians LLC-AtriumFranklin, United StatesNo longer taking part
- Saint Luke's Cancer Institute - FruitlandFruitland, United StatesTaking people
- UF Health Cancer Institute - GainesvilleGainesville, United StatesTaking people
- Illinois CancerCare-GalesburgGalesburg, United StatesTaking people
- Northwestern Medicine Cancer Center DelnorGeneva, United StatesTaking people
- Aurora Health Care Germantown Health CenterGermantown, United StatesTaking people
- NorthShore University HealthSystem-Glenbrook HospitalGlenview, United StatesTaking people
- Northwestern Medicine Glenview Outpatient CenterGlenview, United StatesTaking people
- Southeastern Medical Oncology Center-GoldsboroGoldsboro, United StatesTaking people
- CTCA at Western Regional Medical CenterGoodyear, United StatesTaking people
- Aurora Cancer Care-GraftonGrafton, United StatesTaking people
- Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, United StatesTaking people
- Trinity Health Grand Rapids HospitalGrand Rapids, United StatesTaking people
- Northwestern Medicine Grayslake Outpatient CenterGrayslake, United StatesTaking people
- Benefis Sletten Cancer InstituteGreat Falls, United StatesTaking people
- UCHealth Greeley HospitalGreeley, United StatesTaking people
- Aurora BayCare Medical CenterGreen Bay, United StatesTaking people
- Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, United StatesTaking people
- Saint Vincent Hospital Cancer Center Green BayGreen Bay, United StatesTaking people
- Cone Health Cancer CenterGreensboro, United StatesTaking people
- Cone Health Cancer Center at Drawbridge ParkwayGreensboro, United StatesTaking people
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, United StatesTaking people
- BI-LO Charities Children's Cancer CenterGreenville, United StatesTaking people
- Miami Valley Cancer Care and InfusionGreenville, United StatesTaking people
- Prisma Health Cancer Institute - ButternutGreenville, United StatesTaking people
- Prisma Health Cancer Institute - EastsideGreenville, United StatesTaking people
- Prisma Health Cancer Institute - FarisGreenville, United StatesTaking people
- Saint Francis Cancer CenterGreenville, United StatesTaking people
- Saint Francis HospitalGreenville, United StatesTaking people
- Prisma Health Cancer Institute - GreerGreer, United StatesTaking people
- Baptist Cancer Center-GrenadaGrenada, United StatesTaking people
- Zangmeister Center Grove CityGrove City, United StatesTaking people
- Gulfport Memorial HospitalGulfport, United StatesNo longer taking part
- Memorial Sloan Kettering WestchesterHarrison, United StatesTaking people
- Ingalls Memorial HospitalHarvey, United StatesTaking people
- Advocate South Suburban HospitalHazel Crest, United StatesTaking people
- Lehigh Valley Hospital-HazletonHazleton, United StatesTaking people
- Essentia Health Hibbing ClinicHibbing, United StatesTaking people
- Hayworth Cancer CenterHigh Point, United StatesTaking people
- NorthShore University HealthSystem-Highland Park HospitalHighland Park, United StatesTaking people
- Hawaii Cancer Care Inc - Waterfront PlazaHonolulu, United StatesTaking people
- Kapiolani Medical Center for Women and ChildrenHonolulu, United StatesTaking people
- Queen's Cancer Cenrer - POB IHonolulu, United StatesTaking people
- Queen's Cancer Center - KuakiniHonolulu, United StatesTaking people
- Queen's Medical CenterHonolulu, United StatesTaking people
- Straub Clinic and HospitalHonolulu, United StatesTaking people
- University of Hawaii Cancer CenterHonolulu, United StatesTaking people
- Lyndon Baines Johnson General HospitalHouston, United StatesTaking people
- UT MD Anderson Cancer CenterHouston, United StatesTaking people
- Houston Methodist HospitalHouston, United StatesNo longer taking part
- Houston Methodist West HospitalHouston, United StatesNo longer taking part
- Methodist Willowbrook HospitalHouston, United StatesNo longer taking part
- Edwards Comprehensive Cancer CenterHuntington, United StatesTaking people
- Swedish Cancer Institute-IssaquahIssaquah, United StatesTaking people
- Mayo Clinic in FloridaJacksonville, United StatesTaking people
- Southeastern Medical Oncology Center-JacksonvilleJacksonville, United StatesTaking people
- Mercyhealth Hospital and Cancer Center - JanesvilleJanesville, United StatesTaking people
- Regional Cancer Center at Johnson City Medical CenterJohnson City, United StatesTaking people
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, United StatesTaking people
- Beacon KalamazooKalamazoo, United StatesTaking people
- Beacon Kalamazoo Cancer CenterKalamazoo, United StatesTaking people
- Bronson Methodist HospitalKalamazoo, United StatesTaking people
- West Michigan Cancer CenterKalamazoo, United StatesTaking people
- Logan Health Medical CenterKalispell, United StatesTaking people
- Aurora Cancer Care-Kenosha SouthKenosha, United StatesTaking people
- Kettering Medical CenterKettering, United StatesTaking people
- Greater Dayton Cancer CenterKettering, United StatesNo longer taking part
- Illinois CancerCare-Kewanee ClinicKewanee, United StatesTaking people
- Kingman Regional Medical CenterKingman, United StatesTaking people
- Ballad Health Cancer Care - KingsportKingsport, United StatesTaking people
- Gundersen Lutheran Medical CenterLa Crosse, United StatesTaking people
- UC San Diego Moores Cancer CenterLa Jolla, United StatesTaking people
- Providence Regional Cancer System-LaceyLacey, United StatesTaking people
- Northwestern Medicine Lake Forest HospitalLake Forest, United StatesTaking people
- Monmouth Medical Center Southern CampusLakewood, United StatesTaking people
- Fairfield Medical CenterLancaster, United StatesTaking people
- University of Michigan Health - Sparrow LansingLansing, United StatesTaking people
- Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, United StatesTaking people
- OptumCare Cancer Care at CharlestonLas Vegas, United StatesTaking people
- Summerlin Hospital Medical CenterLas Vegas, United StatesTaking people
- OptumCare Cancer Care at Fort ApacheLas Vegas, United StatesNo longer taking part
- CommonSpirit Saint Joseph Medical Center - East LexingtonLexington, United StatesTaking people
- University of Kentucky/Markey Cancer CenterLexington, United StatesTaking people
- AMG Libertyville - OncologyLibertyville, United StatesTaking people
- Condell Memorial HospitalLibertyville, United StatesTaking people
- Cooperman Barnabas Medical CenterLivingston, United StatesTaking people
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, United StatesTaking people
- Monmouth Medical CenterLong Branch, United StatesTaking people
- Cedars-Sinai Medical CenterLos Angeles, United StatesTaking people
- The Angeles Clinic and Research Institute - West Los Angeles OfficeLos Angeles, United StatesTaking people
- Medical Center of the RockiesLoveland, United StatesTaking people
- Covenant Medical Center-LakesideLubbock, United StatesNo longer taking part
- Henry Ford Saint John Hospital - Macomb MedicalMacomb, United StatesTaking people
- Illinois CancerCare-MacombMacomb, United StatesTaking people
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, United StatesTaking people
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, United StatesTaking people
- Schoolcraft Memorial HospitalManistique, United StatesTaking people
- OhioHealth Mansfield HospitalMansfield, United StatesTaking people
- Fairview Clinics and Surgery Center Maple GroveMaple Grove, United StatesTaking people
- Saint John's Hospital - HealtheastMaplewood, United StatesTaking people
- Aurora Bay Area Medical Group-MarinetteMarinette, United StatesTaking people
- OhioHealth Marion General HospitalMarion, United StatesTaking people
- Marshfield Medical Center-MarshfieldMarshfield, United StatesTaking people
- Contra Costa Regional Medical CenterMartinez, United StatesNo longer taking part
- Memorial HospitalMarysville, United StatesTaking people
- Carle Physician Group-Mattoon/CharlestonMattoon, United StatesTaking people
- Hillcrest Hospital Cancer CenterMayfield Heights, United StatesNo longer taking part
- Loyola University Medical CenterMaywood, United StatesTaking people
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, United StatesTaking people
- Riddle Memorial HospitalMedia, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-MemphisMemphis, United StatesTaking people
- UH Seidman Cancer Center at Lake Health Mentor CampusMentor, United StatesTaking people
- Saint Luke's Cancer Institute - MeridianMeridian, United StatesTaking people
- East Jefferson General HospitalMetairie, United StatesNo longer taking part
- UM Sylvester Comprehensive Cancer Center at KendallMiami, United StatesTaking people
- University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, United StatesTaking people
- Woodland Cancer Care CenterMichigan City, United StatesTaking people
- UH Seidman Cancer Center at Southwest General HospitalMiddleburg Heights, United StatesNo longer taking part
- Memorial Sloan Kettering MonmouthMiddletown, United StatesTaking people
- Aurora Cancer Care-MilwaukeeMilwaukee, United StatesTaking people
- Aurora Saint Luke's Medical CenterMilwaukee, United StatesTaking people
- Aurora Sinai Medical CenterMilwaukee, United StatesTaking people
- NYU Langone Hospital - Long IslandMineola, United StatesTaking people
- Abbott-Northwestern HospitalMinneapolis, United StatesTaking people
- Marshfield Medical Center - MinocquaMinocqua, United StatesTaking people
- Community Medical CenterMissoula, United StatesTaking people
- University of South Alabama Mitchell Cancer InstituteMobile, United StatesTaking people
- UPMC Hillman Cancer Center - MonroevilleMonroeville, United StatesTaking people
- West Virginia University HealthcareMorgantown, United StatesTaking people
- Knox Community HospitalMount Vernon, United StatesTaking people
- SSM Health Good SamaritanMount Vernon, United StatesTaking people
- ProHealth D N Greenwald CenterMukwonago, United StatesTaking people
- Trinity Health Muskegon HospitalMuskegon, United StatesTaking people
- Saint Alphonsus Cancer Care Center-NampaNampa, United StatesTaking people
- Saint Luke's Cancer Institute - NampaNampa, United StatesTaking people
- Vanderbilt Breast Center at One Hundred OaksNashville, United StatesTaking people
- Vanderbilt University/Ingram Cancer CenterNashville, United StatesTaking people
- Houston Methodist Saint John HospitalNassau Bay, United StatesNo longer taking part
- ThedaCare Regional Medical Center - NeenahNeenah, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, United StatesTaking people
- Rutgers Cancer Institute of New JerseyNew Brunswick, United StatesTaking people
- UC Comprehensive Cancer Center at Silver CrossNew Lenox, United StatesTaking people
- ThedaCare Cancer Care - New LondonNew London, United StatesTaking people
- Ochsner Medical Center JeffersonNew Orleans, United StatesTaking people
- University Medical Center New OrleansNew Orleans, United StatesNo longer taking part
- Cancer Center of Western WisconsinNew Richmond, United StatesTaking people
- Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, United StatesTaking people
- Memorial Sloan-Kettering Cancer CenterNew York, United StatesTaking people
- Mount Sinai HospitalNew York, United StatesTaking people
- Helen F Graham Cancer CenterNewark, United StatesTaking people
- Licking Memorial HospitalNewark, United StatesTaking people
- Medical Oncology Hematology Consultants PANewark, United StatesTaking people
- Providence Newberg Medical CenterNewberg, United StatesTaking people
- CTCA at Southeastern Regional Medical CenterNewnan, United StatesNo longer taking part
- Corewell Health Lakeland Hospitals - Niles HospitalNiles, United StatesTaking people
- Carle BroMenn Medical CenterNormal, United StatesTaking people
- Carle Cancer Institute NormalNormal, United StatesTaking people
- University of Miami Sylvester Comprehensive Cancer Center at Sole MiaNorth Miami, United StatesTaking people
- Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, United StatesTaking people
- Cancer Care Center of O'FallonO'Fallon, United StatesTaking people
- Advocate Christ Medical CenterOak Lawn, United StatesTaking people
- ProHealth Oconomowoc Memorial HospitalOconomowoc, United StatesTaking people
- Saint Vincent Hospital Cancer Center at Oconto FallsOconto Falls, United StatesTaking people
- University of Oklahoma Health Sciences CenterOklahoma City, United StatesTaking people
- Nebraska Medicine-Village PointeOmaha, United StatesNo longer taking part
- University of Nebraska Medical CenterOmaha, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-OntarioOntario, United StatesTaking people
- Children's Hospital of Orange CountyOrange, United StatesTaking people
- Saint Joseph Hospital - OrangeOrange, United StatesTaking people
- Providence Willamette Falls Medical CenterOregon City, United StatesTaking people
- Northwestern Medicine Orland ParkOrland Park, United StatesTaking people
- University of Chicago Medicine-Orland ParkOrland Park, United StatesTaking people
- ThedaCare Cancer Care - OshkoshOshkosh, United StatesTaking people
- Vince Lombardi Cancer Clinic - OshkoshOshkosh, United StatesTaking people
- Illinois CancerCare-Ottawa ClinicOttawa, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-OxfordOxford, United StatesTaking people
- Mercy Health - Paducah Cancer CenterPaducah, United StatesNo longer taking part
- Stanford Cancer Institute Palo AltoPalo Alto, United StatesTaking people
- VA Palo Alto Health Care SystemPalo Alto, United StatesTaking people
- Paoli Memorial HospitalPaoli, United StatesTaking people
- Advocate Lutheran General HospitalPark Ridge, United StatesTaking people
- Illinois CancerCare-PekinPekin, United StatesTaking people
- Capital Health Medical Center-HopewellPennington, United StatesNo longer taking part
- Illinois CancerCare-PeoriaPeoria, United StatesTaking people
- Mercy Health - Perrysburg HospitalPerrysburg, United StatesTaking people
- Illinois CancerCare-PeruPeru, United StatesTaking people
- Fox Chase Cancer CenterPhiladelphia, United StatesTaking people
- Pennsylvania HospitalPhiladelphia, United StatesTaking people
- Thomas Jefferson University HospitalPhiladelphia, United StatesTaking people
- Mayo Clinic Hospital in ArizonaPhoenix, United StatesNo longer taking part
- OhioHealth Pickerington Methodist HospitalPickerington, United StatesTaking people
- UPMC Hillman Cancer CenterPittsburgh, United StatesTaking people
- UPMC-Magee Womens HospitalPittsburgh, United StatesTaking people
- UPMC-Passavant HospitalPittsburgh, United StatesTaking people
- UM Sylvester Comprehensive Cancer Center at PlantationPlantation, United StatesTaking people
- Michigan Healthcare Professionals PontiacPontiac, United StatesTaking people
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, United StatesTaking people
- Oregon Health and Science UniversityPortland, United StatesTaking people
- Providence Portland Medical CenterPortland, United StatesTaking people
- Providence Saint Vincent Medical CenterPortland, United StatesTaking people
- Southern Ohio Medical CenterPortsmouth, United StatesTaking people
- Kootenai Clinic Cancer Services - Post FallsPost Falls, United StatesTaking people
- Illinois CancerCare-PrincetonPrinceton, United StatesTaking people
- Roger Williams Medical CenterProvidence, United StatesTaking people
- Women and Infants HospitalProvidence, United StatesTaking people
- Aurora Cancer Care-RacineRacine, United StatesTaking people
- Duke Women's Cancer Care RaleighRaleigh, United StatesTaking people
- Rapid City Regional HospitalRapid City, United StatesNo longer taking part
- Corewell Health Reed City HospitalReed City, United StatesTaking people
- Annie Penn Memorial HospitalReidsville, United StatesTaking people
- Renown Regional Medical CenterReno, United StatesTaking people
- Valley Medical CenterRenton, United StatesTaking people
- Marshfield Medical Center-Rice LakeRice Lake, United StatesTaking people
- Henrico Doctor's HospitalRichmond, United StatesTaking people
- VCU Massey Cancer Center at Stony PointRichmond, United StatesTaking people
- VCU Massey Comprehensive Cancer CenterRichmond, United StatesTaking people
- Reid HealthRichmond, United StatesNo longer taking part
- Virginia Cancer InstituteRichmond, United StatesNo longer taking part
- Carilion Roanoke Memorial HospitalRoanoke, United StatesTaking people
- Mayo Clinic in RochesterRochester, United StatesTaking people
- Pluta Cancer CenterRochester, United StatesNo longer taking part
- Mercyhealth Cancer Institute - RockfordRockford, United StatesTaking people
- Mercy Cancer Center - RocklinRocklin, United StatesTaking people
- Phelps Health Delbert Day Cancer InstituteRolla, United StatesNo longer taking part
- Corewell Health Children'sRoyal Oak, United StatesTaking people
- Corewell Health William Beaumont University HospitalRoyal Oak, United StatesTaking people
- Mercy Cancer Center - SacramentoSacramento, United StatesTaking people
- MyMichigan Medical Center SaginawSaginaw, United StatesTaking people
- Oncology Hematology Associates of Saginaw Valley PCSaginaw, United StatesNo longer taking part
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, United StatesTaking people
- Corewell Health Lakeland Hospitals - Saint Joseph HospitalSaint Joseph, United StatesTaking people
- Heartland Regional Medical CenterSaint Joseph, United StatesTaking people
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, United StatesTaking people
- Regions HospitalSaint Paul, United StatesTaking people
- United HospitalSaint Paul, United StatesTaking people
- Sainte Genevieve County Memorial HospitalSainte Genevieve, United StatesTaking people
- Sharp Memorial HospitalSan Diego, United StatesTaking people
- UC San Diego Medical Center - HillcrestSan Diego, United StatesTaking people
- UCSF Medical Center-Mission BaySan Francisco, United StatesNo longer taking part
- Kootenai Clinic Cancer Services - SandpointSandpoint, United StatesTaking people
- Essentia Health SandstoneSandstone, United StatesTaking people
- Saint John's Cancer InstituteSanta Monica, United StatesTaking people
- Guthrie Medical Group PC-Robert Packer HospitalSayre, United StatesTaking people
- MaineHealth Maine Medical Center- ScarboroughScarborough, United StatesTaking people
- Swedish Medical Center-First HillSeattle, United StatesTaking people
- Prisma Health Cancer Institute - SenecaSeneca, United StatesTaking people
- Sidney Kimmel Cancer Center Washington TownshipSewell, United StatesTaking people
- ThedaCare Cancer Care - ShawanoShawano, United StatesTaking people
- Saint Vincent Hospital Cancer Center at SheboyganSheboygan, United StatesTaking people
- Sheboygan Physicians GroupSheboygan, United StatesTaking people
- Vince Lombardi Cancer Clinic-SheboyganSheboygan, United StatesTaking people
- Memorial Hospital EastShiloh, United StatesTaking people
- Sanford Cancer Center Oncology ClinicSioux Falls, United StatesTaking people
- Sanford USD Medical Center - Sioux FallsSioux Falls, United StatesTaking people
- Robert Wood Johnson University Hospital SomersetSomerville, United StatesTaking people
- Memorial Hospital of South BendSouth Bend, United StatesNo longer taking part
- VCU Community Memorial Health CenterSouth Hill, United StatesTaking people
- MaineHealth Cancer Care and IV Therapy - South PortlandSouth Portland, United StatesTaking people
- Baptist Memorial Hospital and Cancer Center-DesotoSouthhaven, United StatesTaking people
- Baystate Medical CenterSpringfield, United StatesTaking people
- CoxHealth South HospitalSpringfield, United StatesTaking people
- Mercy Hospital SpringfieldSpringfield, United StatesTaking people
- Southern Illinois University School of MedicineSpringfield, United StatesTaking people
- Springfield ClinicSpringfield, United StatesTaking people
- Springfield Memorial HospitalSpringfield, United StatesTaking people
- Springfield Regional Cancer CenterSpringfield, United StatesTaking people
- Springfield Regional Medical CenterSpringfield, United StatesTaking people
- Mercy Hospital Saint LouisSt Louis, United StatesTaking people
- Mercy Hospital SouthSt Louis, United StatesTaking people
- Missouri Baptist Medical CenterSt Louis, United StatesTaking people
- Siteman Cancer Center at Christian HospitalSt Louis, United StatesTaking people
- Siteman Cancer Center-South CountySt Louis, United StatesTaking people
- Washington University School of MedicineSt Louis, United StatesTaking people
- Marshfield Medical Center-River Region at Stevens PointStevens Point, United StatesTaking people
- Tufts Medical Center Cancer Center StonehamStoneham, United StatesTaking people
- Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, United StatesTaking people
- Houston Methodist Sugar Land HospitalSugar Land, United StatesNo longer taking part
- Missouri Baptist Sullivan HospitalSullivan, United StatesTaking people
- Aurora Medical Center in SummitSummit, United StatesTaking people
- State University of New York Upstate Medical UniversitySyracuse, United StatesTaking people
- MyMichigan Medical Center TawasTawas City, United StatesTaking people
- Scott and White Memorial HospitalTemple, United StatesTaking people
- Montefiore Medical Center - Moses CampusThe Bronx, United StatesTaking people
- Montefiore Medical Center-Einstein CampusThe Bronx, United StatesTaking people
- Montefiore Medical Center-Weiler HospitalThe Bronx, United StatesTaking people
- Houston Methodist The Woodlands HospitalThe Woodlands, United StatesNo longer taking part
- Mercy Health - Saint Anne HospitalToledo, United StatesTaking people
- Toledo Clinic Cancer Centers-ToledoToledo, United StatesNo longer taking part
- Community Medical CenterToms River, United StatesTaking people
- Munson Medical CenterTraverse City, United StatesTaking people
- Corewell Health Beaumont Troy HospitalTroy, United StatesTaking people
- Upper Valley Medical CenterTroy, United StatesTaking people
- Saint Luke's Cancer Institute - Twin FallsTwin Falls, United StatesTaking people
- Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, United StatesTaking people
- Carle Cancer CenterUrbana, United StatesTaking people
- Essentia Health Virginia ClinicVirginia, United StatesTaking people
- Providence Saint Mary Regional Cancer CenterWalla Walla, United StatesTaking people
- Epic Care Cyberknife CenterWalnut Creek, United StatesNo longer taking part
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, United StatesTaking people
- Illinois CancerCare - WashingtonWashington, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, United StatesTaking people
- UW Cancer Center at ProHealth CareWaukesha, United StatesTaking people
- ThedaCare Cancer Care - WaupacaWaupaca, United StatesTaking people
- Aurora Cancer Care-Milwaukee WestWauwatosa, United StatesTaking people
- Aurora West Allis Medical CenterWest Allis, United StatesTaking people
- Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, United StatesNo longer taking part
- OhioHealth Westerville Medical Campus/Westerville Cancer CenterWesterville, United StatesTaking people
- Saint Ann's HospitalWesterville, United StatesTaking people
- Marshfield Medical Center - WestonWeston, United StatesTaking people
- Presbyterian Intercommunity HospitalWhittier, United StatesNo longer taking part
- Asplundh Cancer PavilionWillow Grove, United StatesTaking people
- Wake Forest University Health SciencesWinston-Salem, United StatesTaking people
- Woodland Memorial HospitalWoodland, United StatesTaking people
- Lankenau Medical CenterWynnewood, United StatesTaking people
- University of Michigan Health - WestWyoming, United StatesTaking people
- North Star Lodge Cancer Center at Yakima Valley Memorial HospitalYakima, United StatesTaking people
- Saint Elizabeth Youngstown HospitalYoungstown, United StatesNo longer taking part
- Huron Gastroenterology PCYpsilanti, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, United StatesTaking people
- Genesis Healthcare System Cancer Care CenterZanesville, United StatesTaking people
- Midwestern Regional Medical CenterZion, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Cancer Institute (NCI)
- Trial code
- NCT05564377
- Record updated
- 2 November 2026
- Original description
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) and have progressed on at least one line of standard systemic therapy or have no standard treatment that has been shown to prolong overall survival may be candidates for these trials. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with some genetic changes or abnormalities (mutations) may benefit from treatment that targets that particular genetic mutation. ComboMATCH is designed to match patients to a treatment that may work to control their tumor and may help doctors plan better treatment for patients with locally advanced or advanced solid tumors.Read full original descriptionShow less
Molecular Analysis for Combination Therapy Choice (ComboMATCH)
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) and have progressed on at least one line of standard systemic therapy or have no standard treatment that has been shown to prolong overall survival may be candidates for these trials. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with some genetic changes or abnormalities (mutations) may benefit from treatment that targets that particular genetic mutation. ComboMATCH is designed to match patients to a treatment that may work to control their tumor and may help doctors plan better treatment for patients with locally advanced or advanced solid tumors.
Inclusion: Patient must have measurable disease; Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status between 0-2 OR patient must have Lansky performance status of >= 50% or Karnofsky performance status of >= 50%; Patient must be deemed potentially eligible for a ComboMATCH Treatment Trial as assessed by the enrolling provider; All patients must have sequencing results available from a National Cancer Institute (NCI) credentialed Designated Laboratory (DL); Patients must have locally advanced or advanced histologically documented solid tumors requiring therapy and meet one of the following criteria:; Patients must have progressed on at least one line of standard systemic therapy OR; Patients whose disease has no standard treatment that has been shown to prolong overall survival; Patient must meet one of the following requirements:; Patients 18 years and older who have tumor amenable to minimal risk image-guided or direct vision biopsy and must be willing and able to undergo a tumor biopsy to obtain samples for research if the patient is to enroll in a ComboMATCH treatment trial OR; Patients 18 years and older who do not have disease that is biopsiable at minimal risk to the patient must confirm availability of an archival tumor tissue specimen for submission for research if the patient enrolls to a ComboMATCH Treatment Trial. This tumor tissue must meet the following criteria:; Tissue must have been collected within 12 months prior to registration to the EAY191 Registration Trial; Patient must not have had a Response Evaluation Criteria in Solid Tumors (RECIST) response (complete response [CR] or partial response [PR]) to any intervening therapy after collection of the tissue; Formalin-fixed paraffin-embedded tumor tissue block(s) or slides must be available OR; Patients under 18 years old must confirm availability of an archival tumor tissue specimen for submission for research if patient enrolls to a ComboMATCH Treatment Trial. This tumor tissue must meet the following criteria:; Formalin-fixed paraffin-embedded tumor tissue block(s) or slides must be available; NOTE: See specific ComboMATCH Treatment Trial protocol for tissue collection and management instructions. Performance of the mandatory research biopsy or submission of pre-trial formalin-fixed paraffin-embedded (FFPE) and collection and submission of the blood specimens for the integrated studies will be performed under the consent authority of the specific treatment trial protocol to which the patient is registered. No procedures to collect specimens for research only are to be performed for patients registered to the EAY191 Registration Trial only; NOTE: Each ComboMATCH Treatment Trial contains specific eligibility criteria. If patient is found to not be eligible for the assigned ComboMATCH Treatment Trial, indication of ineligibility will trigger re-evaluation and potential assignment to another Treatment Trial.