Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients
Key facts
- Who runs it
- Jona Hattangadi-Gluth
- Where
- San Diego, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 300 people, planned
- Started
- Jan 2015
- Expected to end
- Dec 2030
- Type of study
- Observational
- Record updated
- 10 June 2026
Who can take part
- Age
- 18 years to 99 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Patients 18 years or older
- Karnofsky performance status (KPS) ≥70
- Life expectancy of ≥1 year
- Primary brain tumor patients who will receive fractionated partial brain RT
- Able to complete neurocognitive assessments
Who cannot take part
- Prior brain RT
- Inability to undergo MRI with contrast
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Where in United States
- Moores Cancer CenterSan Diego, United StatesContact: Lara J RoseTaking people
About the trial
What the trial wants to find out
In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.
The group in the trial
- Primary brain tumour patients receiving RT
Primary brain tumor patients are screened at time of consultation for this observational study, and the study population is diverse across sex/gender, and racial/ethnic groups.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Longitudinal Prospective Study of Neurocognitive Outcomes and Multimodal Quantitative Neuroimaging Outcomes in Primary Brain Tumor Patients Receiving Brain Radiotherapy
- Fit questions
- Built from NCT05576103, who can take part
- Record updated
- 10 June 2026