Studying Tumor Tissue to Find New Targets in Metastatic Prostate Cancer
Studies tumor tissue from adults with spread prostate cancer to find new drug targets.
Plain-language title generated from the registry record
Registry title: Novel Therapy Target in Metastatic Prostate Cancer
Key facts
- Where
- Shanghai, ChinaSee the site
Where in China
- Fudan University Shanghai Cancer CenterShanghai, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fudan University
- Trial code
- NCT05577689
- Record updated
- 5 June 2025
- Original description
The aim of this study is to use multiomics sequencing to explore the molecular characteristics of metastatic prostate cancer (mPCa), especially metastatic castration-resistant prostate cancer (mCRPC). At the same time, mCRPC models will be constructed, including organoids and animal models, serving as a basic and translational research platform to help identify novel drug targets for mPCa.Read full original descriptionShow less
Combining Multi-omics Analysis and Organoid Models to Search for Novel Therapy Target in Metastatic Prostate Cancer
The aim of this study is to use multiomics sequencing to explore the molecular characteristics of metastatic prostate cancer (mPCa), especially metastatic castration-resistant prostate cancer (mCRPC). At the same time, mCRPC models will be constructed, including organoids and animal models, serving as a basic and translational research platform to help identify novel drug targets for mPCa.
Inclusion: Histologically confirmed prostate cancer; metastatic disease confirmed by image examination; Patients who can undergo surgery or biopsy for prostate cancer; Able to provide informed consent.
Exclusion: Not accessible to surgery sample; Patients diagnosed with other types of cancer besides prostate cancer; Patients fail to provide informed consent; Other situation that researchers think are unsuitable for this study.