A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen Planus

Who can take part

• Clinical diagnosis of LP with predominant cutaneous involvement
• IGA score of 3 or 4 at screening and baseline
• Baseline LP-related Itch NRS score ≥ 4
• Willingness to avoid pregnancy or fathering children

Who cannot take part

• Concurrent conditions and history of other diseases:; Variants of LP deemed by the investigators to be inappropriate for topical treatment, including but not limited to predominant mucosal (such as oral or vaginal) LP; Active ongoing inflammatory diseases of the skin other than LP that might confound the evaluation of LP lesions or compromise participant safety; Any other concomitant skin disorder (eg, generalized erythroderma such as Netherton's syndrome), pigmentation, or extensive scarring that in the opinion of the investigator may interfere with the evaluation of LP lesions or compromise participant safety; Immunocompromised (eg, lymphoma, acquired immunodeficiency syndrome, or Wiskott-Aldrich syndrome); Chronic or acute infection requiring treatment with systemic antibiotics, antivirals, antiparasitics, antiprotozoals, or antifungals within 2 weeks before baseline; Active acute bacterial, fungal, or viral skin infection (eg, herpes simplex, herpes zoster, chickenpox, clinically infected AD, or impetigo) within 1 week before baseline
• Laboratory values outside of the protocol-defined criteria
• Pregnant or lactating participants, or those considering pregnancy during the period of their study participation
• Other exclusive criteria may apply