Measuring Radioactive Iodine Uptake Before and After a Low Iodine Diet
Compares iodine uptake before and after a diet in thyroid cancer.
Plain-language title generated from the registry record
Registry title: Iodine Uptake After a Low Iodine Diet
Key facts
- Where
- Groningen, NetherlandsSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05599139, who can take part
Where in Netherlands
- UMCGGroningen, NetherlandsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Medical Center Groningen
- Trial code
- NCT05599139
- Record updated
- 6 February 2026
- Original description
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days.Read full original descriptionShow less
The Uptake of Radioactive Iodine Before and After a Low Iodine Diet in Patients With Differentiated Thyroid Carcinoma
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days.
The main question it aims to answer is:
• What is the difference in iodine uptake before and after a LID of 7 days?
Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.
Inclusion: Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline; Patients have to be fit to adhere to the study protocol; Patients have to be able to read and understand the Dutch language.
Exclusion: Patients receiving iodinated contrast < 3 months before the LID; Patients prepared for ablation therapy with rhTSH; Renal impairment, EGFR <30ml/min/1,73m2; Age < 18 years; Patients using amiodarone; Pregnancy.