Compares two keyhole weight-loss operations in adults with severe obesity
Compares a stomach and intestine bypass with stomach reduction in adults with obesity.
Plain-language title generated from the registry record
Registry title: Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity
Key facts
- Where
- Oslo and Tønsberg, NorwaySee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 60 years old?
Source: NCT05611697, who can take part
Where in Norway
- Oslo University HospitalOslo, NorwayTaking people
- The Morbid Obesity Center, Vestfold Hospital TrustTønsberg, NorwayTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oslo University Hospital
- Trial code
- NCT05611697
- Record updated
- 18 May 2026
- Original description
This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.Read full original descriptionShow less
Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity: A Randomized Trial
This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.
Inclusion: Morbid obesity at referral for bariatric surgery (i.e. a body-mass index [BMI] of ≥35 kg/m2 with obesity-related comorbid conditions or ≥40 kg/m2 with or without such comorbidities); Age 20-60 years; Previous failed attempts of weight loss; Norwegian speaking patients.
Exclusion: Previous or current gastroesophageal reflux symptoms with daily use of antireflux medication. Patients are also excluded if preoperative manometry identifies a hiatal hernia (≥4cm in axial length) or if preoperative upper endoscopy identifies esophagitis grade C or D (LA classification), peptic stricture, Barrett's esophagus, or esophageal carcinoma; A history of major abdominal or bariatric surgery (excluding appendectomy, cholecystectomy, and sectio); Established disabling cardiopulmonary disease, ongoing treatment for cancer, long-term steroid use, and conditions believed to be associated with poor adherence after surgery; BMI ≥55 kg/m2; Achalasia; Pregnancy.