Prediction of Long-term Outcome in Aortic Stenosis After Valve Intervention

The registry criteria, word for word

What the trial wants to find out

Patients with severe aortic stenosis accepted for transcatheter intervention or open surgery are included before the intervention, and then followed up with clinical visits during the first year after intervention. Imaging with echocardiography and computed tomography (CT) are performed together with additional imaging with magnetic resonance imaging (MRI) and Positron emissions tomography (PET)-CT in a subgroup of the study population. Blood samples, physical performance and questionnaires with focus on frailty and heart failure are also collected at each visit. A follow up with information of the outcomes after 2-5 years will be performed through national registries.

The 2 groups in the trial

• Preserved heart function

  The group will be defined as preserved left ventricular ejection fraction (LVEF) with and without hypertrophy and with and without reduced global longitudinal strain (GLS).

  Treatment: There is no intervention since it is an observational study patients are treated according to clinical praxis

• Reduced heart function

  The group will be defined as reduced LVEF

  Treatment: There is no intervention since it is an observational study patients are treated according to clinical praxis