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Exercise Types and Sleep Quality in People With Parkinson's Disease

Tests cardiovascular, resistance and combined exercise programs for sleep in adults with Parkinson's disease.

Plain-language title generated from the registry record
Registry title: Exercise to Improve Sleep in Parkinson's Disease

Key facts

Where
Laval and Montreal, CanadaSee the 3 sites

Where in Canada

  • Jewish Rehabilitation HospitalLaval, CanadaTaking people
  • Cummings CentreMontreal, CanadaNot yet recruiting
  • Human Brain Control of Locomotion LaboratoryMontreal, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
McGill University
Trial code
NCT05644327
Record updated
13 March 2026
Original description
This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.Read full original descriptionShow less

The Effects of Different Exercise Modalities on Sleep Quality and Architecture in People With Parkinson's Disease

This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.

Inclusion: Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn \& Yahr Scale stages 0.5-3.5); On a stable dosage of medication during the previous month; Having poor sleep quality defined as a score > 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality.

Exclusion: Participating in an exercise or drug trial during the period of the study; Having atypical parkinsonism, dementia, stroke, or any other neurological condition; Presenting severe untreated obstructive sleep apnea (OSA); Having a Montreal Cognitive Assessment (MoCA) score <18; Having a Beck Depression Inventory score >31; Having absolute contraindications to exercise; Having severe osteoporosis; Exceeding the physical activity levels recommended for the general population (≥150 minutes/week of moderate-intensity or ≥75 minutes/week of vigorous-intensity cardiovascular activity) and/or strengthening activities ≥2 days/week.

ClinicalTrials.gov NCT05644327