Studies eye blood vessels in people with high blood pressure, diabetes or cholesterol problems
Uses eye scans to track blood vessel changes in adults with these common conditions.
Plain-language title generated from the registry record
Registry title: Retinal Vascular Manifestations in Patients With Common Internal Diseases on OCTA Tomography Angiography
Key facts
- Where
- Beijing, ChinaSee the site
Where in China
- Beijing Tongren HospitalBeijing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Beijing Tongren Hospital
- Trial code
- NCT05644548
- Record updated
- 25 September 2025
- Original description
Hypertension, diabetes mellitus, and dyslipidemia are common internal diseases, and all diseases are atherosclerosis risk factors. Previous studies applied color fundus photography to analyze retinal vascular changes (including exudation, hemorrhage, neovascularization, etc.) in patients with hypertension or diabetes, but the examination results could not be quantified.Read full original descriptionShow less
Retinal Vascular Manifestations in Patients With Common Internal Diseases on Optical Coherence Tomography Angiography
Hypertension, diabetes mellitus, and dyslipidemia are common internal diseases, and all diseases are atherosclerosis risk factors. Previous studies applied color fundus photography to analyze retinal vascular changes (including exudation, hemorrhage, neovascularization, etc.) in patients with hypertension or diabetes, but the examination results could not be quantified.
This study intends to apply optical coherence tomography angiography (OCTA) to examine retinal vessels. This method has the following advantages: 1) It can quantify vascular changes, and 2) It is noninvasive and reproducible for patients' follow-up.
This study was designed to investigate retinal vascular changes in patients with hypertension, diabetes, and dyslipidemia on OCTA. We will collect the patients' general information (gender, age), comorbidities, medications, blood lipids, blood glucose, carotid ultrasound, ankle-brachial index, ambulatory blood pressure monitoring, color fundus photography, and OCTA results. We will follow up with the patients for five years and conduct the mentioned examinations once a year. We will also investigate the correlation between systemic atherosclerosis (such as coronary artery stenosis, and carotid artery stenosis) and retinal vasculopathy in patients with these diseases.
Inclusion: Patients with hypertension; Or patients with diabetes; Or patients with dyslipidemia; Agree to participate in this study.
Exclusion: Patients with malignant tumors; Patients with autoimmune diseases; Patients with immunodeficiency disease; Disagree to participate in this study.