Transcranial Magnetic Stimulation Therapy in Neuropathic Painful Spinal Cord Injury Patients
Key facts
- Who runs it
- Afyonkarahisar Health Sciences University
- Where
- Afyonkarahisar, TürkiyeSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 60 people, planned
- Started
- 15 Nov 2022
- Planned end
- 31 Mar 2026
- Type of study
- Interventional, 2 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- High-frequency real-time rTMS protocol
- Sham rTMS Protocol
- Record updated
- 9 March 2026
Who can take part
- Age
- 20 years to 70 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 19 criteriaShow less
Who can take part
- Between the ages of 20-70, who applied to the AFSU Physical Medicine and Rehabilitation inpatient service with the diagnosis of spinal cord injury and
- Having spinal cord injury with neurophatic pain at least six months ago,
- Able to follow two-stage verbal commands,
- Agreeing to participate in the study voluntarily and regularly,
- Patients who are medically stable (no previous myocardial infarction, no musculoskeletal problems) will be included in our study
Who cannot take part
- Presence of in-ear implant,
- Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, arrhythmia, pacemaker) and uncontrolled hypertension,
- Epilepsy,
- History of antiepileptic drug use,
- With malignancy and active infection,
- Infection on the skin in the application area,
- Having inflammatory disease,
- Having a brain lesion or a history of drug use that will affect the seizure threshold,
- Intracranial metal object,
- Cognitive dysfunction,
- Lower extremity peripheral nerve injury,
- Having an open wound,
- Orthopedic injuries that can limit maximum effort contractions,
- Patients with increased intracranial pressure or uncontrolled migraine will not be included
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 70 years old?
Where in Türkiye
- AfyonkarahisarAfyonkarahisar, TürkiyeContact: Nuran EYVAZ, MDTaking people
About the trial
What the trial wants to find out
The aim of our study is to investigate the effect of high-frequency Repetitive Transcranial Magnetic Stimulation(rTMS) therapy applied to the dorsolateral PFC (DLPFC) area on neuropathic pain in patients with spinal cord injury. In this area, there are very few studies on the effectiveness of rTMS treatment added to medical treatment in neuropathic pain. In addition, the number of studies comparing the effect of rTMS therapy applied to the DLFPC area is very few.
The 2 groups in the trial
- High-frequency real-time rTMS protocolTreatment being tested
It was planned to apply a total of 1200 beats to the dorsolateral prefrontal cortex daily at a frequency of 10 HZ at 110% intensity of the motor threshold for 15 sessions.
- Sham rTMS ProtocolSham treatment, for comparison
It was planned to apply daily sham rTMS to the dorsolateral prefrontal cortex for 15 sessions.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effect of Repetative Transcranial Magnetic Stimulation Therapy on Neuropathic Pain in Patients With Spinal Cord Injury
- Fit questions
- Built from NCT05645003, who can take part
- Record updated
- 9 March 2026