Ultrasound Study of Brain Blood Flow and Stiffness in Newborns
Uses contrast ultrasound and elastography to study brain blood flow in newborns with brain injury.
Plain-language title generated from the registry record
Registry title: Neonatal Brain Ultrasound With CEUS and Elastography
Key facts
- Where
- Turku, FinlandSee the site
- Phase
- Phase 3
Where in Finland
- Turku University HospitalTurku, FinlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Turku University Hospital
- Trial code
- NCT05648812
- Record updated
- 15 January 2026
- Original description
The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain perfusion. We use contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography to evaluate the state of brain perfusion. We will study neonates recruited from the Neonatal Units of Turku University Hospital.Read full original descriptionShow less
Contrast Enhanced Ultrasound and Elastography of the Neonatal Brain
The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain perfusion. We use contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography to evaluate the state of brain perfusion. We will study neonates recruited from the Neonatal Units of Turku University Hospital.
Inclusion: Babies less than 7 months treated at the neonatal units of Turku University hospital.
Exclusion: Difficult congenital malformations that need surgical treatment; Pre-known genetic disease; Medical history of SonoVue hypersensitivity; Uncontrolled systemic hypertension; Central nervous system tumors; Weight less than 2,5 kg during examination; Systolic pulmonary artery pressure > 90 mmHg; Unstable cardiovascular state.