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Measuring Blood Flow in Heart Artery Small Vessels for Chest Pain Patients

Checks heart artery blood flow and pressure in adults with angina during catheter procedures.

Plain-language title generated from the registry record
Registry title: A Study of Pressure Waveform Analysis in Coronary Artery-II

Key facts

Where
Hsinchu, TaiwanSee the site

Where in Taiwan

  • National Taiwan University Hospital Hsin Chu BranchHsinchu, TaiwanTaking people

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Trial details

Who runs it
National Taiwan University Hospital Hsin-Chu Branch
Trial code
NCT05672706
Record updated
5 January 2023
Original description
The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are:Read full original descriptionShow less

A Study of Pressure Waveform Analysis in Coronary Artery-II

The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are:

* Repeatability of CFR and IMR assessment while hyperemia with intracoronary adenosine was administered. * Evaluate the correlation of the intrinsic signal of coronary waveform versus physiologic ischemia, while defined by fractional flow reserve(FFR) and CFR respectively. * The predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes in 3 years Participants will undergo FFR, CFR, and IMR assessments in the catheterization laboratory of the National Taiwan University Hospital Hsin-Chu Branch, then clinical events follow up for 3 years.

Inclusion: Participants with angina.

Exclusion: Severe valvular heart disease; History of asthma; Heart rate less than 50 beats per minute; systolic blood pressure less than 90 mmHg.

ClinicalTrials.gov NCT05672706