Tests scalp electrical stimulation to reduce seizures in people with epilepsy
Tests scalp electrical stimulation to see if it lowers seizure frequency and intensity.
Plain-language title generated from the registry record
Registry title: Study of Transcranial Direct Current Stimulation to Treat Epilepsy
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- Mayo Clinic MinnesotaRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT05673915
- Record updated
- 28 January 2026
- Original description
The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.Read full original descriptionShow less
Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy
The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.
Inclusion: Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy; Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%; Has not had control with at least 2 anti-seizure medicines; Able to maintain a constant medication for duration of the study (rescue meds allowed); Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.
Exclusion: A disease likely to progress over course of the study; Psychogenic non-epileptic seizures; Suicide attempt or psychiatric hospitalization past 2 years; A skin condition interfering with scalp electrodes or allergy to silver; Women will verify not pregnant, and if applicable, have a serum pregnancy test; Implanted devices (e.g. pacemakers)-except VNS, which is allowed.