Tests a ketone ester added to treatment for children with prolonged seizures
Tests added ketone ester in children with seizures that resist standard treatment.
Plain-language title generated from the registry record
Registry title: Exogenous Ketone Esters for Refractory Status Epileptics
Key facts
- Where
- Sohag, EgyptSee the site
- Phase
- Phase 2/3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 1 and 10 years old?
Source: NCT05674552, who can take part
Where in Egypt
- Department of Pediatrics at Sohag University HospitalSohag, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sohag University
- Trial code
- NCT05674552
- Record updated
- 27 November 2024
- Original description
This study aims to investigate the efficacy of add-on exogenous ketone esters for the treatment of children with refractory generalized convulsive status epilepticusRead full original descriptionShow less
Efficacy of Exogenous Ketone Esters for Children With Refractory Convulsive Status Epileptics
This study aims to investigate the efficacy of add-on exogenous ketone esters for the treatment of children with refractory generalized convulsive status epilepticus
Inclusion: Refractory Generalized convulsive status epilepticus.
Exclusion: Current or recent (within the last 24 hours) propofol therapy; Intake of carbonic-anhydrase inhibitors; Failure to obtain informed consent; Associated severe disease condition, including hepatic, renal, respiratory, cardiac, gastrointestinal, endocrinal, and immune systems; Allergies or any other contraindication to exogenous ketone esters; Ketosis (βHB > 2 mmol/L); Recent intake of exogenous ketones, ketogenic diet, or any dietary restrictions/modifications; Hemodynamic or cardio-respiratory instability; Traumatic brain injury; Hypo-/hyperglycemia; Metabolic acidosis; Malnutrition/obesity; Limitations to nasogastric tube feeding; Inborn errors of metabolism.