NCT05680844Completed
Peripheral Treg Cell Senescence & Serum Total Cholesterol Level
Observational Study of the Correlation Between Peripheral Treg Cell Senescence and Serum Total Cholesterol Level
Source: ClinicalTrials.gov · Last updated 8 Apr 2025
Brief summary (registry, in English)
Hypercholesterolemia is a risk factor for the occurrence and development of atherosclerosis. Recent animal studies have found that increased serum cholesterol level is associated with peripheral Treg cell senescence, but clinical evidence is still lacking. The purpose of this study is to analyze the correlation between human peripheral Treg cell senescence and serum total cholesterol level using clinical blood samples, thus laying a foundation for the establishment of novel therapeutic strategies for atherosclerosis based on the regulation of Treg cell senescence.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 200 (actual)
- First submitted
- 23 Dec 2022
- Start date
- 1 Jan 2023
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Tianjin Medical University
- Diseases
- Familial hypercholesterolaemia
- NCT number
- NCT05680844
What you commit to
- Study type: Observational
- Participants enrolled: 200
- From 1 Jan 2023 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute and severe diseases in the last 3 months, including but not limited to, acute myocardial infarction, acute cerebral infarction, cerebral hemorrhage, circulatory failure, respiratory failure (internal diseases), trauma requiring hospitalization, or undergoes surgery under general anesthesia (surgical diseases).
- History of severe diseases, including but not limited to, tumors, serious hematological diseases, serious cardiopulmonary diseases (interventional therapy for coronary artery disease, atrial fibrillation, chronic obstructive pulmonary disease, etc.), renal failure, liver failure, old stroke with serious sequelae.
Other
- Pregnant or lactating women.
- Have participated in clinical trials in the past 3 months.
- The investigator considers that not appropriate for inclusion.
Who the study is looking for
- Age ≥ 30 and ≤ 60 years old with independent behavior ability.
- The participants need to fully understand the purpose and content of the study, and voluntarily participate in the study and sign the informed consent.
Age in the registry: 30 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tianjin Medical University General Hospital Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.