Blood Marker GDF-15 and Heart Damage After Stroke
Studies a blood marker and heart tests in adults with ischemic stroke.
Plain-language title generated from the registry record
Registry title: Stroke-induced Myocardial Dysfunction: Role of GDF-15 (SMOG-15) Clinical Work Package
Key facts
- Where
- Dijon, FranceSee the site
Where in France
- Chu Dijon BourgogneDijon, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre Hospitalier Universitaire Dijon
- Trial code
- NCT05683873
- Record updated
- 22 October 2026
- Original description
The aim of this study is to analyze the relationship between the blood biomarker GDF-15 and heart damage after stroke.Read full original descriptionShow less
Stroke-induced Myocardial Dysfunction: Role of GDF-15 (SMOG-15) Clinical Work Package
The aim of this study is to analyze the relationship between the blood biomarker GDF-15 and heart damage after stroke.
It is being conducted in France, in the Neurology Department of the Dijon University Hospital (Burgundy). The research is interventional because a biological blood test will be performed, as well as a heart rhythm recording and several cardiac echograms during the hospitalization of the participants and during the follow-up consultation scheduled 4 to 6 months after the stroke.
A total of 130 stroke patients will participate in this study.
Participation includes 4 visits:
* Inclusion visit (within 24 hours of the first stroke symptoms) * visit 1 (within 24 to 72 hours of stroke) * visit 2 (within 48 hours of visit 1) * Visit 3 (approximately 4-6 months post-stroke)
Inclusion: Adult with acute symptomatic cerebral infarction documented by brain imaging on admission (cerebral angioscan or cerebral MRI); Whose first symptoms appeared within 24 hours before inclusion; Whose consent to participate in this study was obtained from the patient or a close relative.
Exclusion: Person with acute heart failure, suspected infective endocarditis, STEMI, or concurrent pulmonary embolism; Person with a history of symptomatic stroke, either ischemic or hemorrhagic; Anyone with a history of heart disease including: atrial fibrillation or flutter (known or discovered on admission), chronic heart failure, pacemaker, defibrillator, or other cardiac devices; A person who is not a member or beneficiary of a social security system; Person deprived of liberty; Person subject to a legal protection measure (curatorship, guardianship); Person subject to a legal protection measure; Pregnant, parturient or breastfeeding woman.