Helping adults with HIV in Botswana quit smoking using counseling and varenicline
Tests counseling and varenicline to help adults with HIV stop smoking.
Plain-language title generated from the registry record
Registry title: Botswana Smoking and Abstinence Reinforcement Trial
Key facts
- Where
- Francistown, Good Hope, Kanye, Mahalapye, Mochudi, Palapye, Sefhare, Serowe, Thamaga, and Tutume, BotswanaSee the 15 sites
- Phase
- Phase 4
Where in Botswana
- Itekeng ClinicFrancistown, BotswanaNo longer taking part
- Masego ClinicFrancistown, BotswanaNo longer taking part
- Nyangabgwe Referral HospitalFrancistown, BotswanaNo longer taking part
- Goodhope Primary HospitalGood Hope, BotswanaNo longer taking part
- Kanye Adventist HospitalKanye, BotswanaNo longer taking part
- Airstrip ClinicMahalapye, BotswanaNo longer taking part
- Mahalapye District HospitalMahalapye, BotswanaNo longer taking part
- Morwa ClinicMochudi, BotswanaNo longer taking part
- Kediretswe ClinicPalapye, BotswanaNo longer taking part
- Palpye Primary HospitalPalapye, BotswanaNo longer taking part
- Sefhare Primary HospitalSefhare, BotswanaNo longer taking part
- Sekgoma District HospitalSerowe, BotswanaNo longer taking part
- Serowe ClinicSerowe, BotswanaNo longer taking part
- Thamaga Primary HospitalThamaga, BotswanaNo longer taking part
- Tutume Primary HospitalTutume, BotswanaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Maryland, Baltimore
- Trial code
- NCT05694637
- Record updated
- 9 January 2026
- Original description
Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths. The investigators plan to use an intervention called Screening, Brief Intervention and Referral to Treatment (SBIRT) to help people to quit smoking and also a drug called varenicline. Apart from helping people to stop smoking, the investigators will also test to see how task shifting can be used to help people stop smoking in a sustainable way. Finally, the investigators will estimate the cost of the intervention.Read full original descriptionShow less
Botswana Smoking and Abstinence Reinforcement Trial
Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths. The investigators plan to use an intervention called Screening, Brief Intervention and Referral to Treatment (SBIRT) to help people to quit smoking and also a drug called varenicline. Apart from helping people to stop smoking, the investigators will also test to see how task shifting can be used to help people stop smoking in a sustainable way. Finally, the investigators will estimate the cost of the intervention.
Inclusion: HIV infected; Self reported current daily smoker; Age 18 and older; Engaged in HIV care as defined by being on ART for at least 6 months; Willing/able to provide informed consent in English or Setswana.
Exclusion: Less than 18 years of age; Pregnant; Unable or cognitively impaired to provide consent.