Tracks safety of vagus nerve stimulation for stroke recovery
Follows adults with chronic ischemic stroke receiving vagus nerve stimulation with rehabilitation.
Plain-language title generated from the registry record
Registry title: Vagal Nerve Stimulation in Enhanced Stroke Recovery: The VALOR Registry
Key facts
- Where
- New York, United StatesSee the site
Where in United States
- Icahn School of Medicine at Mount SinaiNew York, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Icahn School of Medicine at Mount Sinai
- Trial code
- NCT05694663
- Record updated
- 8 May 2026
- Original description
Vagal Nerve Stimulation is a novel proven therapy for patients with chronic ischemic stroke. The primary objective of this registry is to assess the safety of vagal nerve stimulation for stroke recovery through monitoring the occurrence of serious adverse events associated with the surgical procedure or subsequent paired rehabilitation protocol. This registry will monitor patients undergoing VNS for stroke recovery in the Mount Sinai Health System and collect clinical and procedural details, objective outcomes, and patient-reported outcomes associated with vagal nerve stimulation for stroke recovery.Read full original descriptionShow less
Vagal Nerve Stimulation in Enhanced Stroke Recovery: The VALOR Registry
Vagal Nerve Stimulation is a novel proven therapy for patients with chronic ischemic stroke. The primary objective of this registry is to assess the safety of vagal nerve stimulation for stroke recovery through monitoring the occurrence of serious adverse events associated with the surgical procedure or subsequent paired rehabilitation protocol. This registry will monitor patients undergoing VNS for stroke recovery in the Mount Sinai Health System and collect clinical and procedural details, objective outcomes, and patient-reported outcomes associated with vagal nerve stimulation for stroke recovery.
Inclusion: Provision of signed and dated informed consent form; Stated willingness to comply with all procedures in the VNS-Enhanced Stroke Recovery Program; Aged 18 or older; History of ischemic stroke; Upper extremity weakness; Planned to undergo VNS implantation.
Exclusion: Unfavorable candidacy for device implant surgery (e.g., history of adverse reactions to anesthetics, poor surgical candidate in surgeon's opinion, prior injury to the vagus nerve etc.); Medical or mental instability (diagnosis of personality disorder, psychosis, or substance abuse) that would prevent the subject from meeting protocol timeline.