Music and brain stimulation for disorders of consciousness and stroke
Tests music listening combined with gentle brain stimulation in adults with consciousness disorders or stroke.
Plain-language title generated from the registry record
Registry title: Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
Key facts
- Where
- Bari, ItalySee the site
Where in Italy
- Istituti Clinici Scientifici MaugeriBari, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituti Clinici Scientifici Maugeri SpA
- Trial code
- NCT05706831
- Record updated
- 10 November 2026
- Original description
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are:Read full original descriptionShow less
Music Intervention and Transcranial Electrical Stimulation for Treating Neurological Diseases
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are:
* to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress.
Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.
Inclusion: Age > 18 years; Post-stroke aphasia; Post-stroke neglect; Patients with disorders of consciusness (DOC).
Exclusion: Previous stroke; use of alcohol and drugs; no hystory of neurological disease; No hystory of psychiatric disease; premorbid dementia; No auditory injury.