NCT05707663Active, not recruiting
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile Onset Huntington's Disease (JoHD)
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: * Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)? * Can reliable biomarkers for JoHD be found in brain structure and function? Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations who are at-risk for HD and who have been diagnosed with HD as adults.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 37 (actual)
- First submitted
- 16 Dec 2022
- Start date
- 1 Jan 2020
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- University of Iowa
- Diseases
- Huntington's disease
- NCT number
- NCT05707663
What you commit to
- Study type: Observational
- Participants enrolled: 37
- From 1 Jan 2020 to the primary completion date, 31 Aug 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of head trauma, brain tumor, seizures or epilepsy unrelated to JoHD
- History of major surgery or serious chronic medical conditions other than JoHD
Other
- Metal in body
Who the study is looking for
- Clinical diagnosis of JoHD
- Aged 4-30
Age in the registry: 4 years to 30 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Health Science Center at Houston Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| University of Iowa Hospitals and Clinics, Department of Psychiatry Coordinator of this site? Confirm its status | Iowa City | United States | Unknown status |
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| Children's Hospital of Philadelphia with the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| University of California - Davis Coordinator of this site? Confirm its status | Sacramento | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.