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Keyhole Versus Open Surgery to Remove Right-Sided Colon Cancer

Compares keyhole and open surgery to remove right colon cancer in adults.

Plain-language title generated from the registry record
Registry title: Laparoscopic Versus Open Right Colectomy for Right Colon Cancer

Key facts

Where
Larissa, GreeceSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 90 years old?

Source: NCT05713903, who can take part

Where in Greece

  • Department of Surgery, University Hospital of LarissaLarissa, GreeceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Larissa University Hospital
Trial code
NCT05713903
Record updated
4 September 2025
Original description
The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer. This study will be designed as a prospective randomized controlled trial. The comparison of the two techniques will include endpoints regarding the quality characteristics of the specimens and the oncological results. In addition, the effectiveness of the two methods will be evaluated in terms of the early and late postoperative period.Read full original descriptionShow less

Comparison of Laparoscopic Versus Open Right Colectomy for Right Colon Cancer, According to the Complete Mesocolic Excision (CME) Principles: a Prospective Randomized Controlled Trial

The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer. This study will be designed as a prospective randomized controlled trial. The comparison of the two techniques will include endpoints regarding the quality characteristics of the specimens and the oncological results. In addition, the effectiveness of the two methods will be evaluated in terms of the early and late postoperative period.

Inclusion: Histologically confirmed right colon cancer (cecum, ascending colon, hepatic flexure); Surgical resection based on the CME principles; Patient 18 to 90 years old; American Society of Anesthesiologists score ≤III; Τ≤3; Elective operation; Signed informed consent of the patient.

Exclusion: Previous laparotomy; Non elective operation (hemorrhage, perforation, obstruction); Locally advanced disease (T4); Active sepsis or systemic infection; Distant metastases (Stage IV); American Society of Anesthesiologists ≥IV; BMI >35 kg/m2; Untreated physical and mental disability; Pregnancy or breast-feeding; Lack of compliance with the protocol process; Non-granting of signed informed consent.

ClinicalTrials.gov NCT05713903