Investigating Two rTMS Strategies to Treat Cannabis Use Disorder

Who can take part

• Participants must be able to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments
• Participants must be between the ages of 18 and 60
• Participants must meet DSM-5 criteria for at least moderate Cannabis Use Disorder, with use of at least 20 out of the last 28 days
• Participants must express a desire to reduce cannabis use or quit
• Participants must have a positive UDS for cannabis during their enrollment visit (confirming they are regular users)
• The investigative team must believe each participant is a good study-candidate

Who cannot take part

• Participants must not be on any medications that have central nervous system effects that have changed in the past 4-weeks
• Participants must not have any contraindications to receiving rTMS or MRI (e.g. metal implanted above the head, history of seizure, any known brain lesion)
• Participants must not meet moderate or severe use disorder of any other substance with the exception of tobacco/nicotine
• Participants must not have a history of/or current psychotic disorder or bipolar disorder
• Participants must not have any other Axis I condition requiring current treatment
• Participants must not have a history of Dementia or other cognitive impairment
• Participants must not have any unstable general medical conditions
• Participants must not be pregnant or breastfeeding
• Participants must not have active suicidal ideation, or a suicide attempt within the past 180 days