Imaging Eye Blood Flow to Study Glaucoma
Tests a retinal blood flow imaging device in adults with early glaucoma and healthy controls.
Plain-language title generated from the registry record
Registry title: Ocular Blood Flow Imaging for Glaucoma Assessment
Key facts
- Where
- Baltimore, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 88 years old?
Source: NCT05726058, who can take part
Where in United States
- University of Maryland Eye Associates at RedwoodBaltimore, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Maryland, Baltimore
- Trial code
- NCT05726058
- Record updated
- 2 July 2026
- Original description
The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management.Read full original descriptionShow less
Ocular Blood Flow Imaging for Glaucoma Assessment
The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management.
The main question it aims to answer are:
* Can the investigators use blood flow to discriminate between eyes with early-stage glaucoma and variable-matched controls? * Can the investigators validate that the XyCAM FC simultaneously captures both stereo fundus photography and ocular blood flow monitoring?
Participants will be
* measured for their blood pressure, heart rate, height, and weight * dilated with tropicamide * imaged using the XyCAM RI, fundus photography, optical coherence tomography, and standard automated perimetry * imaged using the XyCAM RI while inhaling 100% oxygen through a mask
Inclusion: Age 18 and older with binocular vision; Able to provide informed consent; Patient is a healthy control OR is recommended for glaucoma assessment OR diagnosed with moderate to severe glaucoma in at least one eye as determined by Hodapp Anderson Criteria.
Exclusion: The subject has prior ocular disease other than glaucoma; The subject has anatomically narrow angles or a prior adverse reaction to administration of Tropicamide or fluorescein dye; The subject has diabetes mellitus; The subject has previous ocular surgery other than uncomplicated cataract extraction, laser trabeculoplasty (ALT or SLT), or YAG capsulotomy; The subject has significant media opacity (e.g., a visually significant cataract or significant corneal scar); The subject has more than 15 diopters of refractive error; The subject is a female who is pregnant or nursing.