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Virtual-reality games to help attention problems after brain injury

Tests virtual-reality brain exercises for attention problems in adults with stroke or brain injury.

Plain-language title generated from the registry record
Registry title: Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury

Key facts

Where
Lausanne, SwitzerlandSee the site

Where in Switzerland

  • University of Lausanne HospitalsLausanne, SwitzerlandTaking people

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Trial details

Who runs it
Mindmaze SA
Trial code
NCT05728840
Record updated
17 February 2026
Original description
Stroke is the leading cause of long-term disability with an increasing incidence, especially in young adults. Among the cognitive difficulties following brain damage, deficits in attention are frequent and pervasive, affecting between 46% and 92% of stroke survivors. The current project targets patients with acquired brain injury, including stroke, traumatic brain injury, and brain tumor. The main objective of this study is to evaluate the use and the efficacy of a training program targeting attention and executive function difficulties, using gamified and digitized versions in virtual reality of standard cognitive exercises for patients with brain lesions.Read full original descriptionShow less

Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury

Stroke is the leading cause of long-term disability with an increasing incidence, especially in young adults. Among the cognitive difficulties following brain damage, deficits in attention are frequent and pervasive, affecting between 46% and 92% of stroke survivors. The current project targets patients with acquired brain injury, including stroke, traumatic brain injury, and brain tumor. The main objective of this study is to evaluate the use and the efficacy of a training program targeting attention and executive function difficulties, using gamified and digitized versions in virtual reality of standard cognitive exercises for patients with brain lesions.

Inclusion: Time from stroke onset < 1 month; Objective pathological performance on at least one standardized test or subtest on attention during standard neuropsychological evaluation; Brain injury documented by routine neuroradiological examination (computed tomography or magnetic resonance imaging scan); Able to give informed consent as documented by signature; Age >= 18 years old.

Exclusion: Epilepsy; Major psychiatric co-morbidity; Major neurocognitive deficits (e.g. dementia); Inability or contraindications to undergo the investigated intervention; Incapacity to discriminate colors; General cognitive state preventing to understand and perform the tasks; Decision to not be informed of incidental findings.

ClinicalTrials.gov NCT05728840