Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement
Key facts
- Where
- Beijing, ChinaSee the site
Where in China
- National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing, ChinaContact: Xiangbin Pan, DrTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- China National Center for Cardiovascular Diseases
- Trial code
- NCT05739253
- Record updated
- 10 February 2025
- Original description
The goal of this observational study is to assess the changes of ascending aortic diameter in patients undergoing transcatheter aortic valve replacement. The main questions it aims to answer are:Read full original descriptionShow less
The goal of this observational study is to assess the changes of ascending aortic diameter in patients undergoing transcatheter aortic valve replacement. The main questions it aims to answer are:
1. whether the ascending aortic diameter increases or remains stable after transcatheter aortic valve replacement, especially in patients with preoperative ascending aortic dilatation; 2. the determinants of postoperative ascending aortic dilatation.
Inclusion: Severe aortic stenosis defined as an aortic valve area of 1cm2 or less or an indexed aortic valve area of 0.6cm2/m2 or less; Presence of clinical symptoms defined as a New York Heart Association functional class of 2 or more; High risk of surgical aortic valve replacement; Suitability for a transfemoral vascular access.
Exclusion: History of surgical or transcatheter aortic valve replacement; History of aortic surgery; Connective tissue disorders; Dominant aortic regurgitation.