Trial of a physical activity program with peer support for prostate cancer patients
Tests an exercise program with peer coaching in adults with prostate cancer.
Key facts
- Who runs it
- Centre Hospitalier Universitaire de Saint Etienne
- Where
- Chambéry, Clermont-Ferrand, Grenoble, Le Puy-en-Velay, Lyon, Privas, Roanne, Saint-Etienne, Saint-Priest-en-Jarez, and Valence, FranceSee the 25 sites
- Trial code
- Registry title
- Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients
- Status
- Recruiting
- People taking part
- 850 people, planned
- Started
- 25 Apr 2023
- Expected to end
- 30 Sept 2028
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Acti-Pair program
- Record updated
- 24 November 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for men aged 18 or older who were diagnosed with prostate cancer at least 1 year ago and who are not active enough. It tests a physical activity programme with peer coaching.
- Age
- 18 years or older
- Sex
- Men
- Disease stage
- Prostate cancer diagnosed at least 1 year ago
- Earlier treatment
- Cannot be undergoing treatment, except hormone therapy
Main reasons for not taking part
- Physical activity of 150 minutes per week or more
- Undergoing treatment, except hormone therapy
- Serious heart, breathing or disabling joint problems that make physical activity unsafe
- Deprived of liberty or under guardianship
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Patients:
- Age ≥ 18 years
- Diagnosed with prostate cancer for at least 1 year
- PA practice < 150 minutes per week (considered inactive according to WHO)
- Affiliated or entitled to a social security scheme
- Having received informed information about the study and having co-signed, with the investigator, a consent to participate in the study
Who cannot take part
- Undergoing treatment (except hormone therapy)
- Significant comorbidities contraindicating the practice of physical activity: associated cardiac pathologies, respiratory pathologies, disabling joint pathologies
- For patients:
- Deprived of liberty or under guardianship
Where in France
- Activité Physique Adaptée - CDOS SavoieChambéry, FranceContact: Fabrice DESCOMBES, MD (principal investigator)Not yet recruiting
- CH ChambéryChambéry, FranceContact: Guillaume MORICEAU, MD (principal investigator)Not yet recruiting
- Activité Physique Adaptée - DAHLIR 63Clermont-Ferrand, FranceContact: Joris MARTIN, MD (principal investigator)Not yet recruiting
- CHU Clermont-Ferrand - ONCOLOGIEClermont-Ferrand, FranceContact: Aurore DOUGENot yet recruiting
- CHU Clermont-Ferrand - UrologieClermont-Ferrand, FranceContact: Laurent GUYNot yet recruiting
- Activité Physique Adaptée - CDOS IsèreGrenoble, FranceContact: MDNot yet recruiting
- CHU Grenoble - UrologieGrenoble, FranceContact: Jean-Luc DESCOTES, MDNot yet recruiting
- Activité Physique Adaptée - DAHLIR 43Le Puy-en-Velay, FranceContact: Anaïs CHARRA, MDNot yet recruiting
- CH Le Puy en VelayLe Puy-en-Velay, FranceContact: Corinne BRUCHET, MDNot yet recruiting
- Activité Physique Adaptée - DAHLIR 69Lyon, FranceContact: Julie Julie, MDNot yet recruiting
- CLB - OncologieLyon, FranceContact: Cécile LAUDE, MDNot yet recruiting
- CLB - RadiothérapieLyon, FranceContact: Sofiane HANAYA, MDNot yet recruiting
- HCL - CH Lyon SudLyon, FranceContact: Alain RUFFION, MDNot yet recruiting
- HCL - Hôpital Croix RousseLyon, FranceContact: Claire FALANDRY, MD PhD (principal investigator)Not yet recruiting
- Hcl - Hopital Edouard HerriotLyon, FranceContact: Marc COLOMBEL, PhDNot yet recruiting
- Activité Physique Adaptée - CDOS ArdèchePrivas, FranceContact: Jonathan BAZARD, MD (principal investigator)Not yet recruiting
- CH RoanneRoanne, FranceContact: Lionel VINCENT, MDNot yet recruiting
- Activité Physique Adaptée - DAPAP 42Saint-Etienne, FranceContact: Maël GARROS, MDNot yet recruiting
- CHU Saint-Etienne - OncologieSaint-Etienne, FranceContact: Pierre CORNILLON, MDTaking people
- CHU Saint-Etienne - RadiothérapieSaint-Etienne, FranceContact: Anne-Laure BAREILLE, MDNot yet recruiting
- Hôpital privé de la LoireSaint-Etienne, FranceContact: Stéphane LORIN, MDTaking people
- Clinique du parcSaint-Priest-en-Jarez, FranceContact: Hocine HABCHI, MDNot yet recruiting
- Activité Physique Adaptée - CDOS DrômeValence, FranceContact: Aline CARLIER, MD (principal investigator)Not yet recruiting
- Hôpitaux Drôme Nord - ValenceValence, FranceContact: Thomas POLGUER, MD (principal investigator)Not yet recruiting
- Radiologie Drôme-Ardèche - ValenceValence, FranceContact: Jean-Baptiste GUY, MD (principal investigator)Not yet recruiting
About the trial
What the trial wants to find out
Despite the recognized benefits of physical activity in tertiary prevention, 60-70% of prostate cancer patients are insufficiently active.
Read full original descriptionShow less
Yet 150 minutes of brisk walking per week (new WHO recommendations) is associated with a 29% reduction in cancer mortality and a 57% reduction in recurrence.
Increasing patients' adherence to regular physical activity appears to be a new challenge for personalized cancer care.
Personalized physical activity programmes (1) at home, (2) supported by health professionals, or (3) by peers have shown the effectiveness of regular physical activity.
However, these interventions last less than 6 months and do not allow for long-term sustainability of physical activity.
This study proposes to combine 3 interventions, which aim to initiate and maintain regular physical activity in prostate cancer patients:
* 1-The realization of a personalized and realistic physical activity project via physical activity support devices (sport health centers) * 2-Coaching by a peer (a patient with the same disease who has reached the WHO recommendations for physical activity), who will provide motivational follow-up * 3-Support by health professionals (attending physician) through the prescription of physical activity.
The feasibility of ACTI-PAIR program has been demonstrated, the investigators now wish to evaluate it effectiveness.
The 2 groups in the trial
- Acti-Pair programTreatment being tested
* Motivational support by the peer (a patient with the same pathology who meets the WHO recommendations for physical activity), who will provide motivational follow-up * The implementation of a personalized and realistic physical activity project for the patient via the physical activity support systems (sport health centers) * Support from health professionals (GP) via the prescription of physical activity and from adapted physical activity (APA) professionals
- Usual careNo study treatment, for comparison
The control group will be made up of patients followed up for prostate cancer and benefiting from usual care which consists of giving advice and recommendations for physical activity in consultation, aiming to make patients more active in their daily lives (=usual practice, physical activity to be carried out independently, at home).
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Title Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients - ACTI-PAIR 2 Multicenter, Randomized Stepped-wedge Study
- Plain-language title
- Trial of a physical activity program with peer support for prostate cancer patientsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 24 November 2025