Efficacy and Safety Evaluation of Fecal Microbiota Transplantation in Irritable Bowel Syndrome
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT05740319, who can take part
Where in China
- Zhongshan Hospital,Fudan UniversityShanghai, ChinaContact: Shengdi WuTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Shanghai Zhongshan Hospital
- Trial code
- NCT05740319
- Record updated
- 25 February 2026
- Original description
Participants will be given FMT through oral capsules or nasojejunal tube once a month. After three-time treatment, participants were followed up for three months. Participants complete specific scales to assess improvement in symptoms, emotion and quality of life. Besides, they report adverse effects and collect fecal samples at each visit.Read full original descriptionShow less
Participants will be given FMT through oral capsules or nasojejunal tube once a month. After three-time treatment, participants were followed up for three months. Participants complete specific scales to assess improvement in symptoms, emotion and quality of life. Besides, they report adverse effects and collect fecal samples at each visit.
Inclusion: Patients who fulfilled the Rome IV criteria for the diagnosis of IBS, aged 18-70 years; Patients who have experienced failure of at least 3 conventional therapies for IBS; Absence of red flags such as weight loss, hematochezia.
Exclusion: Immunodeficiency or treatment with immune-modulating medication; Use of probiotics within the previous 3 months or treatment with antibiotics within 1 month prior to study entry; Having undergone any abdominal surgery, with the exception of appendectomy, cholecystectomy, caesarean section and hysterectomy; Presence of severe diseases related to heart, brain, kidney and lung or concomitant malignancies; Psychiatric disorder or unable to cooperate with treatment and follow-up visit; Presence of uncontrolled diabetes, hypertension, thyroid disease or other systemic disease; Pregnant, planning pregnancy or lactating.