Testing for early Parkinson-type protein changes in people with unexplained smell loss
Tests a lab screening method for abnormal protein in adults with unexplained loss of smell.
Plain-language title generated from the registry record
Registry title: Alpha-synuclein Rt-quic and Neurologic Symptoms in Persons With idiOpathic anosMiA
Key facts
- Where
- Copenhagen, DenmarkSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 55 and 75 years old?
Source: NCT05740683, who can take part
Where in Denmark
- Danish Dementia Research CentreCopenhagen, DenmarkTaking people
- Oskar McWilliamCopenhagen, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Danish Dementia Research Centre
- Trial code
- NCT05740683
- Record updated
- 2 October 2024
- Original description
Test of early warning signs and RT-QuIC in patients with idiopathic olfactory dysfunctionRead full original descriptionShow less
Alpha-synuclein Rt-quic and Neurologic Symptoms in Persons With idiOpathic anosMiA
Test of early warning signs and RT-QuIC in patients with idiopathic olfactory dysfunction
Inclusion: Age 55 -75 years of age; Slowly progressing and non-fluctuating iOD; Able to give informed consent and to cooperate as evaluated by the PI; Age 55 -75 years of age; Able to give informed consent; Able to cooperate as evaluated by the PI.
Exclusion: Olfactory dysfunction with response to systemic or local corticosteroids if tried; Current alcohol or drug abuse; Current alcohol or drug abuse; Diagnosed with a neurodegenerative disease or major neurological/psychiatric condition; Anosmia/hyposmia caused by sino-nasal disease (including chronic rhinitis and allergy), after trauma, infection, congenial, olfactory dysfunction due to surgery, or toxins/drugs affecting the olfactory function; Severe nasal cavity abnormalities or infections; Overt signs of dementia or PD; Terminal illness; Diagnosed with neurodegenerative disease or major neurological/psychiatric condition; Overt signs of dementia or PD; Severe nasal cavity abnormalities or infections; Diagnosed with neurodegenerative disease or major neurological/psychiatric condition; Olfactory dysfunction on clinical test.