NCT05746247Completed
Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
The goal of this study is to identify individuals at high risk of FH, and to encourage the appropriate diagnosis and treatment of individuals at high risk of FH through the use of implementation science and behavioral economics principles. Phase 1: Applying the FIND FH tool to the health system EHR and gathering data for pilot development; Phase 2: Pilot development and implementation; Phase 3: Conduct a large-scale pragmatic trial consistent with recommendations and learnings from the pilots in Phase 2
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 610 (actual)
- First submitted
- 17 Feb 2023
- Start date
- 1 Mar 2022
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- University of Pennsylvania
- Diseases
- Familial hypercholesterolaemia
- NCT number
- NCT05746247
What you commit to
- Study type: Interventional
- Participants enrolled: 610
- From 1 Mar 2022 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Already have been clinically diagnosed with FH using the proper ICD-10 code
- Currently see a lipid specialist at Penn Medicine
- Pass study clinician's Study Validity Check
Who the study is looking for
- Must be a patient at Penn Medicine
- Must have been flagged by the FIND FH tool as having a high probability of FH
- First language is English
- Resides in PA or NJ
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pennsylvania Health System Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.