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NCT05746247Completed

Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

Source: ClinicalTrials.gov · Last updated 20 Aug 2026

Brief summary (registry, in English)

The goal of this study is to identify individuals at high risk of FH, and to encourage the appropriate diagnosis and treatment of individuals at high risk of FH through the use of implementation science and behavioral economics principles. Phase 1: Applying the FIND FH tool to the health system EHR and gathering data for pilot development; Phase 2: Pilot development and implementation; Phase 3: Conduct a large-scale pragmatic trial consistent with recommendations and learnings from the pilots in Phase 2

Status (registry)
Completed
Study type
Interventional
Enrollment
610 (actual)
First submitted
17 Feb 2023
Start date
1 Mar 2022
Primary completion date
30 Jun 2026
Lead sponsor
University of Pennsylvania
NCT number
NCT05746247

What you commit to

  • Study type: Interventional
  • Participants enrolled: 610
  • From 1 Mar 2022 to the primary completion date, 30 Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Already have been clinically diagnosed with FH using the proper ICD-10 code
  • Currently see a lipid specialist at Penn Medicine
  • Pass study clinician's Study Validity Check

Who the study is looking for

  • Must be a patient at Penn Medicine
  • Must have been flagged by the FIND FH tool as having a high probability of FH
  • First language is English
  • Resides in PA or NJ

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Pennsylvania Health System
Coordinator of this site? Confirm its status
PhiladelphiaUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.