Studies pain and autonomic symptoms in Parkinson disease and multiple system atrophy
Observes pain, autonomic symptoms and rehabilitation effects in adults with Parkinson disease or MSA.
Plain-language title generated from the registry record
Registry title: Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
Key facts
- Where
- Castel Goffredo, Lumezzane, Milan, Mistretta, Montescano, Pavia, Telese Terme, and Veruno, ItalySee the 9 sites
Where in Italy
- ICS Maugeri - CastelgoffredoCastel Goffredo, ItalyTaking people
- ICS Maugeri - LumezzaneLumezzane, ItalyTaking people
- ICS Maugeri - MilanoMilan, ItalyTaking people
- ICS Maugeri - MistrettaMistretta, ItalyTaking people
- ICS Maugeri - MontescanoMontescano, ItalyTaking people
- ICS Maugeri - PaviaPavia, ItalyTaking people
- ICS Maugeri - Pavia BoezioPavia, ItalyTaking people
- ICS Maugeri - IRCCS of Telese TermeTelese Terme, ItalyTaking people
- ICS Maugeri - VerunoVeruno, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituti Clinici Scientifici Maugeri SpA
- Trial code
- NCT05748028
- Record updated
- 17 April 2026
- Original description
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers.Read full original descriptionShow less
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers.
The main aims are:
Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales.
Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.
Inclusion: Clinical diagnosis of Parkinson's Disease or Multiple System Atrophy according to current international criteria (Gilman S et al, 2008; Postuma RB et al. 2015); Mini-Mental State Examination score at least 10.
Exclusion: assumption of potentially neurotoxic drugs; diabetes mellitus; vascular or pharmacological parkinsonism; hepatic or renal dysmetabolism,; hypothyroidism or hyperthyroidism.