NCT05750147Recruiting
The SMARTER Cardiomyopathy Study
Genetics, Imaging and Artificial Intelligence for Precision Care in Cardiomyopathy
Source: ClinicalTrials.gov · Last updated 6 Mar 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Cardiomyopathies are diseases of the heart muscle. Known genetic factors may account for some cardiomyopathy cases but there is still much to understand about the genetic and environmental causes and how the disease progresses. Finding new ways to diagnose and treat cardiomyopathies could improve the health and well-being of patients with these conditions. This study will collect data from individuals with cardiomyopathy or related heart muscle disease, or with a possible genetic predisposition to cardiomyopathy, and follow them over time to observe the progress of their heart and health. This study will collect DNA, blood samples, and detailed clinical \& lifestyle information at the start of the study, and data collected during routine healthcare visits over time. * learn what causes cardiomyopathy, and therefore how to treat it * understand why cardiomyopathy progresses differently in different people, to improve the ability to recognise who will benefit from different treatments at different times The investigators will collaborate with other centres internationally to collect a large of group of participants with similar cardiomyopathies, providing power to identify new pathways that cause disease and ways of predicting which participants are at risk of having more severe disease.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 23 Jan 2023
- Start date
- Mar 2023
- Primary completion date
- Aug 2027
- Lead sponsor
- Imperial College London
- Diseases
- Hypertrophic cardiomyopathy
- NCT number
- NCT05750147
What you commit to
- Study type: Observational
- Planned participants: 1000
- From Mar 2023 to the primary completion date, Aug 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients without the capacity to provide informed consent
Who the study is looking for
- Adults with the capacity to consent Children with parental/guardian consent Male and Female
- Meeting the following criteria:
- Patients with a confirmed diagnosis of cardiomyopathy or related condition
- Patients with a family member with cardiomyopathy, or a related condition
- Patients with a genetic variant that may predispose to cardiomyopathy, or a related condition
Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kings College Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Guys St Thomas NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.