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Brain Mapping Before Epilepsy Surgery in Children and Young People

Studies brain mapping methods to predict language outcomes after epilepsy surgery in young patients.

Plain-language title generated from the registry record
Registry title: Functional Brain Mapping for Patients with Epilepsy

Key facts

Where
Detroit, United StatesSee the 2 sites

Where in United States

  • Children's Hospital of MichiganDetroit, United StatesTaking people
  • Wayne State UniversityDetroit, United StatesTaking people

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Trial details

Who runs it
Wayne State University
Trial code
NCT05755919
Record updated
26 February 2025
Original description
We aim to determine the clinical utility of 'dynamic tractography': a novel method for visualizing electrical neural transfers that incorporates the underlying white matter tracts and supporting linguistic processing. We will also determine how well objective electrophysiology biomarkers will improve the prediction of language outcomes following epilepsy surgery. This project will ultimately optimize understanding of how the human brain develops its language network dynamics.Read full original descriptionShow less

Functional Brain Mapping in Pediatric Neurosurgery

We aim to determine the clinical utility of 'dynamic tractography': a novel method for visualizing electrical neural transfers that incorporates the underlying white matter tracts and supporting linguistic processing. We will also determine how well objective electrophysiology biomarkers will improve the prediction of language outcomes following epilepsy surgery. This project will ultimately optimize understanding of how the human brain develops its language network dynamics.

Inclusion: Epilepsy surgery with extraoperative intracranial EEG recording with subdural or depth electrodes.

Exclusion: Patients with a malignant brain tumor, or progressive neurodegenerative or metabolic disorders who are not considered candidates for intracranial EEG recording.

ClinicalTrials.gov NCT05755919