Checking for Hidden Cortisol Excess in Diabetes and Obesity
Checks how often hidden high cortisol occurs in adults with type 2 diabetes or obesity.
Plain-language title generated from the registry record
Registry title: Type 2 Diabetes, Obesity and Cortisol Excess
Key facts
- Where
- Milan, Roma, Siena, and Udine, ItalySee the 5 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05759637, who can take part
Where in Italy
- Istituto Auxologico ItalianoMilan, ItalyTaking people
- Niguarda HospitalMilan, ItalyTaking people
- Campus Bio-Medico UniversityRoma, ItalyTaking people
- University of SienaSiena, ItalyTaking people
- Azienda Ospedaliero - Universitaria "Santa Maria della Misericordia" di UdineUdine, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituto Auxologico Italiano
- Trial code
- NCT05759637
- Record updated
- 10 November 2026
- Original description
The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.Read full original descriptionShow less
Type 2 Diabetes, Obesity and Cortisol Excess
The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.
Inclusion: patients with T2D and Obesity.
Exclusion: drugs influencing the HPA axis activity. For inclusion in Group 2 the presence of T2D will be an exclusion criteria; prepuberal onset of hypertension, hormonal hypersecreting adrenal mass,; already known secondary hypertension; conditions associated with increased hypothalamic-pituitary-adrenal (HPA) axis activity, -severe autoimmune/rheumatologic and hematologic diseases, alcoholism, kidney disease (glomerular filtration rate <60); pregnancy/breast feeding,; sleep apnea,; symptoms of hypercortisolism.