Testing how the brain learns two-hand skills after stroke
Studies how adults with acute or subacute stroke learn two-handed movement tasks.
Plain-language title generated from the registry record
Registry title: Bimanual Motor Skill Learning in Acute Stroke
Key facts
- Where
- Yvoir, BelgiumSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT05760846, who can take part
Where in Belgium
- Chu Ucl NamurYvoir, BelgiumTaking people
- University Hospital CHU Dinant Godinne UCLYvoir, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital of Mont-Godinne
- Trial code
- NCT05760846
- Record updated
- 12 August 2026
- Original description
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL.Read full original descriptionShow less
Exploring the Neural Substrates of Proximal and Distal Bimanual Motor Skill Learning Through Robotics and Multimodal Brain Imaging
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL.
The goals of this project are: to determine the neural substrates critical to achieve proximal and distal bimanual motor skill learning (bim-MSkL) by specifying whether (sub)acute stroke to different brain areas (cortical and subcortical) induce specific deficits in bimanual and/or distal bim-MSkL, which behavioral components are involved in bim-MSkL, and whether damage to the motor, sensory and inter-hemispheric pathways specifically impairs proximal and/or distal bim-MSkL.
Inclusion: acute stroke (< 21 days); aged 18-90 years; with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging; 18-90 years.
Exclusion: drug/alcohol abuse; medical history with a previous stroke / relevant neurological deficit; drug/alcohol abuse; multiple strokes / dementia / psychiatric condition; HEALTHY INDIVIDUALS:; psychiatric condition/ dementia; " classical " contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...); difficulty in understanding or executing commands; severe aphasia / cognitive deficits interfering with study; inability to complete the tasks (i.e. full paralysis of the arm).
ACUTE STROKE PATIENTS:.