Brain stimulation tested for headaches and chronic pain after COVID-19
Tests brain stimulation with a mild current in people with long COVID pain.
Plain-language title generated from the registry record
Registry title: Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
Key facts
- Where
- Paiporta and Valencia, SpainSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with persistent (long) COVID who have headaches, migraines or chronic pain. It tests a brain stimulation treatment called tDCS.
- Age
- From 16 years old.
- Sex
- Men and women can join.
- Disease stage
- Persistent COVID after an acute COVID-19 infection that was asymptomatic, mild or severe. At least one of these symptoms is needed: migraines, headaches, chronic pain, neuropathic pain, arthralgia, myalgias.
- Biomarker or test result
- A positive PCR test during the acute phase of COVID-19 is needed.
Main reasons for not taking part
- No positive PCR confirmation in the acute phase of COVID-19
- Persistent COVID without at least one of the listed symptoms
- Pacemaker or defibrillator
- Brain implants
- Cranial fractures
Read by machine on 9 November 2026.
Where in Spain
- Clínica PaiportaPaiporta, SpainTaking people
- Escuela de Doctorado. Universidad Católica de Valencia San Vicente Mártir. (Doctoral School. Catholic University of Valencia San Vicente Mártir)Valencia, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fundación Universidad Católica de Valencia San Vicente Mártir
- Trial code
- NCT05780450
- Record updated
- 15 October 2026
- Original description
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and myalgia, as well as sleep problems. Transcranial direct current stimulation is used in the field of Physiotherapy and Rehabilitation, with results that have proven to be effective for treating patients suffering from symptoms like migraines, headaches, chronic pain, fibromyalgia, or chronic neuropathic pain and insomnia. As you can see, in the case of patients with Long Covid, we find several of these symptoms, so it is suggested that if transcranial direct current therapy (TDCS) gives such good results in relieving these symptoms, why couldn't it give such good results and help just as much in patients with Long Covid, since many of the symptoms are the same, even if the origin or cause is different.Read full original descriptionShow less
Effectiveness of Transcranial Direct Current (tDCS) Treatment in Patients With Persistent Covid Who Present Headaches and Chronic Body Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and myalgia, as well as sleep problems. Transcranial direct current stimulation is used in the field of Physiotherapy and Rehabilitation, with results that have proven to be effective for treating patients suffering from symptoms like migraines, headaches, chronic pain, fibromyalgia, or chronic neuropathic pain and insomnia. As you can see, in the case of patients with Long Covid, we find several of these symptoms, so it is suggested that if transcranial direct current therapy (TDCS) gives such good results in relieving these symptoms, why couldn't it give such good results and help just as much in patients with Long Covid, since many of the symptoms are the same, even if the origin or cause is different.
Inclusion: Patients with Persistent Covid; Men and women; All ages from 16 years old; Patients who passed the Covid in its acute phase in an asymptomatic, mild and severe way.
Exclusion: Patients with brain implants; Patients without confirmation with positive PCR in the acute phase of Covid-19; Patients with Persistent Covid who do not have at least one of these symptoms: migraines, headaches, chronic pain, neuropathic pain, arthralgia, myalgias; Patients with pacemaker / defibrillator; Patients with cranial fractures; Pregnant.