Real World Evidence Study in Subjects With Wilson's Disease

Who can take part

• Willing and able to give informed consent for participation in the study
• Male or female patients, aged 18 years or older as of signing the Informed Consent Form (ICF)
• Able and willing to comply with study procedures and requirements, as judged by the treating physician
• Established diagnosis of Wilson's Disease (Leipzig score >4)
• Either newly diagnosed or with elevated liver enzymes (defined as ALT, AST ≥1.5xULN) or 24-hour urinary copper excretion outside of recommended ranges [chelation range 200-500mcg/24 hr; zinc < 100mcg/24 hr]
• Adequate venous access to allow collection of blood samples

Who cannot take part

• Major systemic disease or other illness that would, in the opinion of the investigator, compromise patient safety or interfere with the collection or interpretation of the study results
• Patients with a New Wilson's Disease Index Score of >7
• In the opinion of the investigator, the patient is likely to be non-compliant or uncooperative for routine clinical visits during the study