Predicting Brain Blood Flow Problems After Heart Surgery With Bypass
Monitors brain blood flow regulation in adults during heart surgery to predict stroke.
Plain-language title generated from the registry record
Registry title: Predicting Cerebrovascular Adverse Events Post Cardiac Surgery
Key facts
- Where
- San Donato Milanese, ItalySee the site
Where in Italy
- IRCCS Policlinico San DonatoSan Donato Milanese, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS Policlinico S. Donato
- Trial code
- NCT05786274
- Record updated
- 6 July 2026
- Original description
The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.Read full original descriptionShow less
Predicting Cerebrovascular Adverse Events Post Cardiac Surgery With Cardiopulmonary Bypass by Means of Cerebral AutoreguLation Indices
The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.
Inclusion: age older than 18 years; spontaneous sinus rhythm; no pregnancy; signed informed consent.
Exclusion: concomitant carotid intervention; autonomic disorders; age lower than 18 years; absence of sinus rhythm; reintervention; contraindication to MRI; pregnancy; impossibility of informed consent.