Studying early signs that may come before multiple sclerosis
Looks for risk factors and body changes before symptoms of multiple sclerosis appear in adults.
Plain-language title generated from the registry record
Registry title: Identifying and Characterizing Preclinical MS
Key facts
- Where
- North Haven, United StatesSee the site
Where in United States
- Yale UniversityNorth Haven, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Yale University
- Trial code
- NCT05787795
- Record updated
- 27 August 2026
- Original description
The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.Read full original descriptionShow less
Identifying and Characterizing Preclinical MS
The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.
Inclusion: Age 18+; Having one or more risk factors for multiple sclerosis, including one or more of the below:; Individuals known to have a radiologically isolated syndrome; Individuals with a family history of multiple sclerosis (first degree family member); Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score.
Exclusion: Ongoing treatment with immunosuppressive medications; Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease; Currently pregnant.