NCT05799118Recruiting
Study of the Role of Genetic Modifiers in Hemoglobinopathies
Source: ClinicalTrials.gov · Last updated 20 Mar 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study will investigate the role of genetic modifiers in hemoglobinopathies through a large-scale, multi-ethnic genome-wide association study (GWAS).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 30000 (estimated)
- First submitted
- 10 Mar 2023
- Start date
- 1 Oct 2022
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- Cyprus Institute of Neurology and Genetics
- Diseases
- Sickle cell disease, Thalassaemia
- NCT number
- NCT05799118
What you commit to
- Study type: Observational
- Planned participants: 30000
- From 1 Oct 2022 to the primary completion date, 30 Sept 2027
- 26 sites in 16 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients treated with stem cell transplantation or genetic therapy.
Age
- Age \< 2 years old at the time of the collection of the phenotypic data.
Other
- Patient or legal representative for minors unwilling or unable to give consent.
Who the study is looking for
- Clinical diagnosis of an inherited hemoglobinopathy, including sickle cell disease (SCD), β-thalassemia, and α-thalassemia; all genotypes will be considered.
- Age ≥ 2 years old at the time of the collection of the phenotypic data.
- There will be no limits on study participants in terms of gender, ethnicity, morbidities.
Age in the registry: 2 years to - · Sex: All · Does not accept healthy volunteers
Sites (26)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lucrecia Paím Maternity Coordinator of this site? Confirm its status | Luanda | Angola | Recruiting |
| University of Buenos Aires Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Not yet recruiting |
| University Hospitals Leuven Coordinator of this site? Confirm its status | Leuven | Belgium | Not yet recruiting |
| Universiti Brunei Darussalam Coordinator of this site? Confirm its status | Brunei | Brunei | Not yet recruiting |
| Larnaca General Hospital Coordinator of this site? Confirm its status | Larnaca | Cyprus | Recruiting |
| Limassol General Hospital Coordinator of this site? Confirm its status | Limassol | Cyprus | Recruiting |
| Archbishop Makarios III Hospital Coordinator of this site? Confirm its status | Nicosia | Cyprus | Recruiting |
| Paphos General Hospital Coordinator of this site? Confirm its status | Paphos | Cyprus | Recruiting |
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Recruiting |
| Hospital Clínico San Carlos Coordinator of this site? Confirm its status | Madrid | Spain | Not yet recruiting |
| Laiko General Hospital Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| Hippokrateio Hospital of Athens Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| National and Kapodistrian University of Athens Coordinator of this site? Confirm its status | Athens | Greece | Not yet recruiting |
| General Hospital of Larissa Coordinator of this site? Confirm its status | Larissa | Greece | Recruiting |
| Emek Medical Centre Coordinator of this site? Confirm its status | Afula | Israel | Not yet recruiting |
| University of Turin Coordinator of this site? Confirm its status | Turin | Italy | Not yet recruiting |
| Ampang Hospital Coordinator of this site? Confirm its status | Ampang | Malaysia | Recruiting |
| Universiti Kebangsaan Malaysia Coordinator of this site? Confirm its status | Bangi | Malaysia | Recruiting |
| Universiti Sains Malaysia Coordinator of this site? Confirm its status | Kota Bharu | Malaysia | Recruiting |
| University of Abuja Coordinator of this site? Confirm its status | Abuja | Nigeria | Recruiting |
| Kaduna State University Coordinator of this site? Confirm its status | Kaduna | Nigeria | Recruiting |
| Ahmadu Bello University Coordinator of this site? Confirm its status | Zaria | Nigeria | Recruiting |
| University of Lahore Coordinator of this site? Confirm its status | Lahore | Pakistan | Not yet recruiting |
| Centro Hospitalar e Universitario de Coimbra Coordinator of this site? Confirm its status | Coimbra | Portugal | Not yet recruiting |
| Boston Children's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Centre Hospitalier Monkole Coordinator of this site? Confirm its status | Kinshasa | Democratic Republic of the Congo | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.