Studies how glaucoma progresses in patients through vision and eye scans
Follows adults with glaucoma over 36 months using vision tests and eye scans.
Plain-language title generated from the registry record
Registry title: Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression
Key facts
- Where
- Milan and Roma, ItalySee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 90 years old?
Source: NCT05801471, who can take part
Where in Italy
- Clinica oculistica Ospedale San PaoloMilan, ItalyTaking people
- Glaucoma Research Center, IRCCS Fondazione "G.B. Bietti"Roma, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centervue SpA
- Trial code
- NCT05801471
- Record updated
- 2 January 2026
- Original description
The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.Read full original descriptionShow less
An Observational Prospective Longitudinal Study for the Clinical Evaluation of Visual Field Change in Glaucoma. An Assessment of Different Models of Progression
The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.
Inclusion: Glaucomatous optic nerve head in both eyes; Age between 40 and 90 years; Best Corrected Visual Acuity ≤ 0.3 [logMar]; Spherical refraction between -6D and +6D; Astigmatism between -2D and +2D.
Exclusion: Any ocular surgery, except for: uncomplicated cataract surgery and/or glaucoma surgery in both eyes performed within 6 months before enrollment; Use of any drug that can interfere with the correct execution of perimetry or that would produce visual field loss; Any ocular pathology that can affect visual field other than glaucoma; Inability to obtain reliable perimetric examinations; Patients with advanced glaucoma for whom, according to the clinician, a 24-2 grid is not advisable to correctly monitor the patient.