Low-carbohydrate diet for blood sugar in people with type 2 diabetes and obesity
Tests a low-carbohydrate diet in adults with short-duration type 2 diabetes.
Plain-language title generated from the registry record
Registry title: Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction
Key facts
- Where
- Stockholm, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 24 and 70 years old?
Source: NCT05801614, who can take part
Where in Sweden
- Center for diabetes, Academic Specialist centerStockholm, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Region Stockholm
- Trial code
- NCT05801614
- Record updated
- 2 January 2024
- Original description
This is a randomized controlled trial to determine whether a low-carbohydrate (LC) diet can lead to normalized blood glucose levels in patients with short duration of type 2 diabetes (T2D). Previous studies have shown that caloric restricted diet leading to weight loss can normalize blood glucose levels in approximately 50% of patients with a short duration of diabetes type 2. However, caloric restriction is difficult to maintain. Less restrictive approaches are needed. The hypothesis in this study is that Low carbohydrate diet can results in normalized blood glucose levels in T2D and can be an alternative to caloric restriction diet, both in the shorter term (3 months) and longer term (15 months). The outcome of this study leading to reduction of HbA1c is important for prevention of diabetes complications.Read full original descriptionShow less
Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction: a Randomized Controlled Trial (CarborCal)
This is a randomized controlled trial to determine whether a low-carbohydrate (LC) diet can lead to normalized blood glucose levels in patients with short duration of type 2 diabetes (T2D). Previous studies have shown that caloric restricted diet leading to weight loss can normalize blood glucose levels in approximately 50% of patients with a short duration of diabetes type 2. However, caloric restriction is difficult to maintain. Less restrictive approaches are needed. The hypothesis in this study is that Low carbohydrate diet can results in normalized blood glucose levels in T2D and can be an alternative to caloric restriction diet, both in the shorter term (3 months) and longer term (15 months). The outcome of this study leading to reduction of HbA1c is important for prevention of diabetes complications.
Inclusion: HbA1c > 48 mmol/mol (with or without medical treatment); less than 6 years since the diagnosis of T2D; BMI ≥ 27 kg/m2 (≥ 25 kg/m2 for Asians).
Exclusion: myocardial infarction within the previous 6 months,; severe or unstable heart failure; other severe diseases including cancer, psychiatric/eating disorders, severe depression - substance abuse,; conditions that may affect the ability of patients to participate in the study; HbA1c concentration of 12% or more (≥108 mmol/mol),; treatment with sulphonyl urea or sodium-glucose-cotrasporter2-inhibitor (SGL2-i),; Insulin deficiency.