The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE
Key facts
- Who runs it
- E-DA Hospital
- Where
- Taiwan1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Recruiting
- People taking part
- 165 people, planned
- Started
- 13 Mar 2023
- Expected to end
- 31 Dec 2026
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- One biopsy
- Three biopsy
- Seattle protocol
- Endoscopy
- Record updated
- 11 May 2023
Who can take part
- Age
- 20 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Adults with columnar-lined esophagus
Who cannot take part
- A prior history of endoscopic treatment for Barrett's Esophagus
- A prior history of upper gastrointestinal malignancy
- A prior history of total or subtotal gastrectomy
- Taking antiplatelet drug or anticoagulant
- Esophageal varices noted during the procedure
- Uncontrolled coagulopathy
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Detections of goblet cells and dysplasia are crucial for diagnosis and determining the surveillance program of Barrett's esophagus (BE). However, the optimal biopsy numbers and their yield rates of intestinal metaplasia (IM) and dysplasia are still uncertain, especially in Asia. The aim of this study was to determine the optimal biopsy protocol of BE.
The 3 groups in the trial
- One biopsyTreatment being tested
Obtain one biopsy specimen at the proximal part of the the longest columnar-lined esophagus for patients with suspected Barrett's Esophagus
Treatment: One biopsy and Endoscopy
- Three biopsyExisting treatment, for comparison
Obtain three biopsy specimens at the proximal, middle and distal part of the longest columnar-lined esophagus for patients with suspected Barrett's Esophagus
Treatment: Three biopsy and Endoscopy
- Seattle protocolSham treatment, for comparison
Obtain 4-quadrant biopsy specimens at intervals of every 1 to 2 cm throughout the the columnar-lined esophagus for patients with suspected Barrett's Esophagus
Treatment: Seattle protocol and Endoscopy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study
- Record updated
- 11 May 2023