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Studying Brain Signals During Walking in Parkinson's Disease

Records brain activity while adults with Parkinson's disease perform walking-related movement tasks.

Plain-language title generated from the registry record
Registry title: Investigating Neural Biomarkers for Gait in Parkinson's Patients

Key facts

Where
Vitznau, SwitzerlandSee the site

Where in Switzerland

  • CereneoVitznau, SwitzerlandTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Swiss Federal Institute of Technology
Trial code
NCT05820074
Record updated
3 December 2024
Original description
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.Read full original descriptionShow less

Investigating Neural Biomarkers for Gait in Parkinson's Patients

This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.

Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.

Inclusion: All participants; must have given informed consent as documented by signature; agree to comply with the study procedures; Healthy control group; no neurological, orthopedic, or rheumatologic disease history; no identified sensory impairment; no epilepsy and self-diagnosed acute or chronic psychiatric disorders; Parkinson's Patients; non-tremor dominant idiopathic PD patients; presence of postural instability (UPDRS >1 for postural instability [17]), gait disturbance, and absence of other causes of reduced balance; Implanted with Percept™ PC neurostimulator; Able to be in the stimulation OFF.

Exclusion: Relevant cognitive impairment, with a score on Montréal Cognitive Assessment (MoCA) < 20; History of physical or neurological condition that interferes with study procedures; Social and/or personal circumstances interfering with the ability to come to the session.

ClinicalTrials.gov NCT05820074