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Studying Memory and Thinking Skills in Young People Treated for Cancer

Follows thinking and brain function in children and young adults during and after chemotherapy.

Plain-language title generated from the registry record
Registry title: Investigating Cognitive Impairment in Young Patients With Cancer Prospectively

Key facts

Where
Copenhagen, DenmarkSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children, teenagers and young adults newly diagnosed with a cancer outside the brain and spinal cord who will get chemotherapy. Each patient is paired with a control person of similar age.

Age
7-29 years at diagnosis. Each control person must be within 24 months of age of the patient.
Sex
All sexes can join.
Disease stage
Newly diagnosed cancer that is not a central nervous system (CNS) cancer, treated with chemotherapy at University Hospital Copenhagen, Rigshospitalet.
Earlier treatment
People cannot have had chemotherapy or radiotherapy before.

Main reasons for not taking part

  • Cannot speak and understand Danish
  • Severe intellectual disability or mental health disorder that hinders taking part
  • Brain metastases
  • Terminal illness
  • Previous chemotherapy or radiotherapy

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 7 and 29 years old?

Source: NCT05840575, who can take part

Where in Denmark

  • RigshospitaletCopenhagen, DenmarkContact: Lisa L Hjalgrim, PhD, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Copenhagen University Hospital, Rigshospitalet
Trial code
NCT05840575
Record updated
3 May 2023
Original description
The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer. The tests include 1) cognitive skills such as memory and attention; 2) the brain's electrical activity; 3) and biological markers related to brain function.Read full original descriptionShow less

A Multidisciplinary Neuroscience Approach to Investigate Cognitive Impairment in Young Patients With Cancer Prospectively

The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer. The tests include 1) cognitive skills such as memory and attention; 2) the brain's electrical activity; 3) and biological markers related to brain function.

The aim of the study is to better understand the trajectories of cognitive functioning and measures that have been associated with cognitive impairment in patients treated with chemotherapy.

Inclusion: Patients who are newly diagnosed with a non-CNS cancer and will undergo chemotherapy at University Hospital Copenhagen, Rigshospitalet; At the age of 7-29 years at diagnosis; Each patient is matched (1:1) with a control participant within 24 months of age. The controls are recruited from the patient's own social circle and can be a friend, partner, or close family (sibling or cousin).

Exclusion: Have had a previous chemotherapy or radiotherapy treatment; Severe intellectual disability or mental health disorder that hinders participation; Terminal illness; Unable to speak and understand Danish; Brain metastases,.

ClinicalTrials.gov NCT05840575