Heart blood flow during fast heartbeats in adults with heart disease
Measures heart blood flow and pressure during paced fast rhythms in adults with heart disease.
Plain-language title generated from the registry record
Registry title: Coronary Flow During Rapid Heart Rates
Key facts
- Where
- London, United KingdomSee the site
Where in United Kingdom
- Imperial College NHS Foundation TrustLondon, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Imperial College London
- Trial code
- NCT05841199
- Record updated
- 27 March 2026
- Original description
The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are:Read full original descriptionShow less
Coronary Epicardial and Microcirculatory Determinants of Ventricular Tachycardia Tolerability
The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are:
1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does treatment of coronary artery disease with stents improve the tolerability of VT?
Participants who are undergoing a clinically indicated coronary angiogram or coronary angioplasty procedure will have measurements of blood pressure, coronary pressure and coronary flow made during pacing at a range of heart rates.
Inclusion: Able to give valid consent; Referred for coronary angiography or coronary angioplasty; Suitable for percutaneous physiological interrogation and PCI when clinically indicated.
Exclusion: Unstable coronary artery disease (acute coronary syndrome); Severe multivessel coronary artery disease suitable for coronary artery bypass grafting; Severe heart valve disease; Severe (NYHA IV) heart failure; Unable to give valid consent; Pregnant or breastfeeding women.