Food Intake and IgA Microbiota in Anorexia Nervosa
Key facts
- Who runs it
- Centre Hospitalier Universitaire de Saint Etienne
- Where
- France1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Terminated
- People taking part
- 14 people enrolled
- Started
- 13 Oct 2023
- Ended
- 2 Feb 2024
- Type of study
- Interventional, 3 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Stool sample
- Food intake evaluation
- Record updated
- 26 November 2025
- Why it stopped
- The coordinating investigator left the sponsor institution and has not been replaced.
Who can take part
- Age
- 18 years to 50 years
- Sex
- Women only
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- female subject, adult, affiliated to a social security system, under the care of the eating disorder department of university hospital of st Etienne
- presenting a diagnosis of pure restrictive anorexia nervosa; For acute subgroup : BMI between 11 and 17.5 kg/m2, patient with a first episode of restrictive anorexia nervosa or with hyperphagic episodes; For the chronic subgroup: BMI between 11 and 17.5 kg/m2, disease evolving for more than 5 years; For Healthy volunteer: BMI between 20 and 24 kg/m², stable weight for the last 3 months, no eating disorder or history of eating disorder
Who cannot take part
- patient with one of the following comorbid disorders: celiac disease, chronic inflammatory bowel disease, lactose intolerance, unstabilized hyperthyroidism, unstabilized diabetes,
- patient does not understand French
- laxative treatment in progress or stopped for less than 15 days,
- antibiotic treatment in the two months preceding inclusion,
- pre-pro or symbiotic treatment in progress or in the month preceding inclusion,
- subject under legal protective measures
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Anorexia nervosa is characterized by intestinal dysbiosis, related to the feeding behavior impairment presented by these patients. Pathophysiologic hypotheses are involving the trouble of the microbiota-gut-brain axis in the field of mental diseases.
The 3 groups in the trial
- Acute anorexia nervosaTreatment being tested
patient diagnose for a first episode of pure restrictive anorexia nervosa will be included. They will have stool sample and Food intake evaluation.
Treatment: Stool sample and Food intake evaluation
- Chronic anorexia nervosaTreatment being tested
Patient diagnose for anorexia nervosa at least 5 years ago and still maintaining a significant thinness will be included. They will have stool sample and Food intake evaluation.
Treatment: Stool sample and Food intake evaluation
- Healthy controlPlacebo, for comparison
Healthy Patient will be included. They will have stool sample and Food intake evaluation.
Treatment: Stool sample and Food intake evaluation
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 26 November 2025