Preparing patients for pancreas surgery before the operation
Tests a pre-surgery program for adults with suspected pancreatic cancer.
Plain-language title generated from the registry record
Registry title: Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas
Key facts
- Where
- 's-Hertogenbosch, Amsterdam, Breda, Eindhoven, Enschede, Groningen, Leeuwarden, Leiden, Maastricht, Nijmegen, Rotterdam, and Utrecht, NetherlandsSee the 13 sites
Where in Netherlands
- Jeroen Bosch Hospital's-Hertogenbosch, NetherlandsTaking people
- Amsterdam University Medical CenterAmsterdam, NetherlandsTaking people
- OLVGAmsterdam, NetherlandsTaking people
- Amphia HospitalBreda, NetherlandsTaking people
- Catharina hospitalEindhoven, NetherlandsTaking people
- Medisch Spectrum TwenteEnschede, NetherlandsTaking people
- University Medical Center GroningenGroningen, NetherlandsTaking people
- Medisch Centrum LeeuwardenLeeuwarden, NetherlandsTaking people
- Leiden University Medical CenterLeiden, NetherlandsTaking people
- Maatricht University Medical CenterMaastricht, NetherlandsTaking people
- Radboud University Medical CenterNijmegen, NetherlandsTaking people
- Erasmus Medical CenterRotterdam, NetherlandsTaking people
- RAKUUtrecht, NetherlandsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Maastricht University Medical Center
- Trial code
- NCT05851534
- Record updated
- 19 October 2026
- Original description
The goal of this stepped-wedge randomized controlled trial is to investigate whether implementation of a best practice program for preoperative optimisation (prehabilitation program) with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors in patients with (suspected) pancreatic cancer will improve outcome. The main questions it will aim to answer are:Read full original descriptionShow less
Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas: the Implementation of Best Practice Before Pancreatic Resection
The goal of this stepped-wedge randomized controlled trial is to investigate whether implementation of a best practice program for preoperative optimisation (prehabilitation program) with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors in patients with (suspected) pancreatic cancer will improve outcome. The main questions it will aim to answer are:
1. Does a prehabilitation program improve the time to functional recovery after pancreatic surgery? 2. Does a prehabilitation program lead to a reduction in the Comprehensive Complication Index after pancreatic surgery?
Inclusion: All patients who are planned for a curative treatment with or without neoadjuvant treatment and elective pancreatic resection in one of the centres of the Dutch Pancreatic Cancer Group (i.e. all centres performing major pancreatic surgery).
Exclusion: acute pancreatic resections (resection scheduled within two weeks); age < 18 years.