Noninvasive Testing of Heart Pacing Therapy in Heart Failure Patients
Tests a noninvasive method to assess cardiac resynchronization therapy in adults with heart failure.
Plain-language title generated from the registry record
Registry title: Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Key facts
- Where
- Oslo, NorwaySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT05868616, who can take part
Where in Norway
- Oslo University HospitalOslo, NorwayTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oslo University Hospital
- Trial code
- NCT05868616
- Record updated
- 15 October 2026
- Original description
Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.Read full original descriptionShow less
Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.
Inclusion: Patients referred for CRT implantation or postoperative control at Oslo University Hospital based on the European Society of Cardiology (ESC) guidelines (2021), and criteria below:; Sinus rhythm; New York Heart Association class II / III heart failure on diagnosis and on optimal medical therapy; Left bundle branch block; QRS duration ≥ 130 ms; Left ventricular ejection fraction ≤ 40%; Patients must have echocardiography examination before implantation; Informed consent obtained from the patient.
Exclusion: Age < 18 years and > 80 years; Ongoing atrial fibrillation; Complete atrioventricular block.