Studies how cancer treatments may affect fertility in people with cancer
Observes whether cancer treatments lower fertility markers in females and males with cancer.
Plain-language title generated from the registry record
Registry title: Impact of Gonadotoxic Therapies on Fertility
Key facts
- Where
- Bern, SwitzerlandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 14 and 50 years old?
Source: NCT05885048, who can take part
Where in Switzerland
- University Women's Hospital (Inselspital)Bern, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Michael von Wolff
- Trial code
- NCT05885048
- Record updated
- 30 July 2026
- Original description
The goal of this observational study is to learn how gonadotoxic treatments (chemotherapies, radiotherapies or immunotherapies) affect the fertility status of participants with cancer.Read full original descriptionShow less
FertiTOX - Platform for Fertility Related Gonadotoxicity of Cancer Therapies
The goal of this observational study is to learn how gonadotoxic treatments (chemotherapies, radiotherapies or immunotherapies) affect the fertility status of participants with cancer.
The main questions it aims to answer are:
* in females, if cancer therapies reduce the Anti-Müllerian hormone (AMH) concentration (ovarian reserve); * in males, if cancer therapies reduce sperm concentration (sperm quality).
Inclusion: Patients with cancer or with benign reasons undergoing chemotherapy and/or radiotherapy of the pelvis (females) and the testicles (males) and/or immune therapy; Willing to participate; Austria: 14-50 years old (adolescents and adults), Germany: 18-50 years old, Switzerland: 14-50 years old (adolescents and adults); Serum hormone analysis before gonadotoxic therapy (females) or serum hormone analysis and sperm analysis before gonadotoxic therapy (males).
Exclusion: Missing consent; Language barrier.