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Lifestyle Program to Support Thinking in Older Adults in China

Tests a multi-part lifestyle program in older adults at higher risk of memory decline.

Plain-language title generated from the registry record
Registry title: A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China

Key facts

Where
Hangzhou, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 60 to 80 who are at risk of cognitive decline but do not have dementia. It tests a lifestyle program against a self-guided one.

Age
60 to 80 years
Sex
All sexes
Disease stage
At risk of cognitive decline with no dementia (AD8 score of 3 or more and/or a low 5-min MoCA score).

Main reasons for not taking part

  • Diagnosed dementia
  • Diagnosed major depression or other neuropsychological diseases
  • Malignant diseases
  • Symptomatic cardiovascular disease or revascularization within one year
  • Severe loss of vision, hearing or communicative ability

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 60 and 80 years old?

Source: NCT05886114, who can take part

Where in China

  • School of Public Health and The Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, ChinaHangzhou, ChinaContact: Xuhao Zhao, MPHTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Zhejiang University
Trial code
NCT05886114
Record updated
6 June 2023
Original description
A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively decelerated cognitive decline in healthy older adults who were at an increased risk of cognitive decline. The HERITAGE study is a 2-year clustered randomized controlled trial (clustered-RCT) that explores the efficacy of a multidomain intervention among 1200 elderly residents with a higher risk of cognitive decline and dementia in Zhejiang Province, ChinaRead full original descriptionShow less

A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China

A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively decelerated cognitive decline in healthy older adults who were at an increased risk of cognitive decline. The HERITAGE study is a 2-year clustered randomized controlled trial (clustered-RCT) that explores the efficacy of a multidomain intervention among 1200 elderly residents with a higher risk of cognitive decline and dementia in Zhejiang Province, China

Inclusion: At risk of cognitive decline: cognitive performance at the mean level or slightly lower than expected for age with no dementia (AD8>=3 and/or 5-min MoCA >, < 11); Free of physical disabilities that preclude participation in the study; Willing to complete all study-related activities for 24 months; Willing to be randomized to either lifestyle intervention group.

Exclusion: Diagnosed dementia patients; Diagnosed major depression or other neuropsychological diseases; Malignant diseases; Symptomatic cardiovascular disease; Revascularization within one year; Severe loss of vision, hearing or communicative ability.

ClinicalTrials.gov NCT05886114